VOL. XXXII.] PHILOSOPHICAL TRANSACTIONS. SSQ 



the 3d or 4th day after the injection, with all the inward and outward signs of 

 the plague that the others had. 



7th. May 6, we collected the bile of this dog dead of the plague, and in- 

 jected it by the crural vein into the blood of another dog, who, presently after 

 the injection, had convulsive motions all over him, which were followed by a 

 lethargic heaviness. On the 2d day after the injection, there appeared a car- 

 buncle on the great pectoral muscle on the right side. The 3d day there arose 

 a considerable bubo on the thigh ; and the dog died the same day. On open- 

 ing the body, we found the forepart of the breast all gangrened under the tegu- 

 ments; and the viscera were full of black clotted blood, as in all the former. The 

 outer surface of the lungs was all purple ; the heart was swelled as large again 

 as usual, with the 4 cavities full of black clotted blood. The- animal lived 3 

 days after the injection, without eating or drinking. 



May JO, we injected the bile of this 2d dog into the crural vein of a 3d, who 

 was soon seized with violent convulsions, and various convulsive motions, for 

 about half a 4- of an hour. When he recovered from these, he appeared dull, and 

 sleepy; and he vomited with violent strainings. The vomiting was followed 

 with a hick up. He eat a little boiled meat, having fasted a good while before 

 the injection was made ; but he vomited it up 2 hours after. He died the 3d 

 day, with the same symptoms of the plague that the other dogs had. 



The State of the Bodies of Persons dead of the Plague, from which the Bile 

 was taken for the Experiments heforementioned. — 1st body. A soldier 25 years of 

 age, of a strong robust constitution, having a flattish bubo on the hollow of 

 the right groin, died delirious. On opening his body, the heart was of an 

 extraordinary size, stuffed with black clotted blood. His lungs covered with a 

 livid purple, and adhering a little to the pleura: the liver was double the natural 

 size, and stuffed with a thick blood : the gall-bladder was full of a black and 

 greenish bile : the dura and pia mater, by their blackness, seetned to have been 

 seized with a gangrenous inflammation : the inner substance of the brain was 

 sprinkled over with an infinite number of small livid spots. 



2d. Mary Pisanne, aged 30 years, of a sanguine habit, had a bubo under 

 her right arm-pit, with a delirium that was followed by a mortal sleepiness. On 

 opening her body, the lungs were in their natural state : the heart was of a 

 prodigious size, full of black coagulated blood, with the left auricle livid and 

 gangrenous : the liver, which was much enlarged, was all covered with purple; 

 and the gall-bladder filled with a black and greenish bile. 



3d. Peter Moulard, of a tender, feeble constitution, about 14 years of age, 

 had a bubo under the hollow of the right groin, very deep, and never came 

 well out : he became delirious with convulsions, in which he died. On open- 



