VOL.. XXXII.] PHILOSOPHICAL TRANSACTIONS. 563 



animal eat and drank heartily after the injection, and did not appear at all in- 

 commoded. The wound bleeding much, we were obliged to fill it with 

 astringent powders, kept in by a pledget and a convenient bandage. Twenty- 

 four hours after, the dressing was taken away, and the wound appeared black 

 and dry. The dog licking it, it suppurated the next day, and afterwards be- 

 came red and well coloured ; and the wound was lessened one half in 8 days ; 

 during which time the dog appeared in perfect health. 



]2th. Eight days after the foregoing experiment, the same dog was killed by 

 about half a drachm of powder of Hungarian vitriol, dissolved in a spoonful of 

 warm water, which we injected into the jugular vein. He died on the spot, 

 with universal convulsions. His heart was found full of grumous blood, re- 

 duced to a kind of thick pap, but without any clots : the bile was yellow, and 

 in small quantity. Not being able to inject it into the crural vein of another 

 dog, because the vein was too small, we contented ourselves with dipping 2 

 compresses in this bile, which we applied and kept under the skin, by 2 wounds 

 made on purpose in this 2d dog : no notable change happened. We observed 

 in these 2 dogs no signs, either internal or external, of the plague. 

 Montpelier, Dec. 4, 1721. 



The Method of Inoculating the Small-Pox in New England, Communicated by 

 Henry Newman, Esq. of the Middle Temple. N° 370, p. 33. 



Two incisions are usually made in the arms, where issues are made, but 

 somewhat larger than for them ; sometimes in one arm, and one leg. 2. Into 

 these are put bits of lint, (the patient at the same time turning his face another 

 way, and guarding his nostrils) which have been dipped in some of the variolous 

 matter taken in a phial, from the pustules of one that has the small-pox of the 

 best sort, and just turning upon him; and so covered down with a plaster of 

 diachylon. 3. Yet we find the variolous matter taken from those that have the 

 inoculated small-pox, altogether as agreeable and effectual as any other. And 

 so we do also what is taken from those that have the confluent sort. 



4. Within 24 hours, we throw away the lint, and the sores are dressed once 

 or twice every 24 hours, with warmed cabbage leaves. 5. The patient con- 

 tinues to conduct himself as at other times ; only not exposing himself to the 

 injuries of the weather, if that be at all tempestuous. 



6. About the 7th day the patient feels the usual symptoms of the small-pox 

 coming on ; and he is now managed as in an ordinary putrid fever. If he can- 

 not hold up, he goes to bed ; if his head ach too much, we put the common 

 poultice to his feet ; if he be very sick at the stomach, we give him a gentle 



4 c 2 



