VOL. XXXVII.] PHILOSOPHICAL TRANSACTIONS, 471 



soon lost the use of his Hinbs. He often attempted to raise himself, and Walk, 

 but still fell down again before he had moved 2 yards from the place. 



After this he vomited plentifully, considering that he had fasted 24 hours ; 

 on which he was seized with a convulsion more violent than any of the former 

 dogs, especially in the muscles that extend the head and spine. These con- 

 vulsions continued about 8 or 10 minutes; on their ceasing, he lay still, breath- 

 ing deeply, though regularly, and seemed to be asleep. In about 10 minutes 

 he raised himself, took some food, and walked about tolerably well. Dr. M. left 

 him, and returning after 3 hours, he found him perfectly recovered. 



Exper. 5. — Oct. 28, Dr. M. injected 1 oz. of the water into the intestinum 

 rectum of a strong spaniel dog, and let him loose. In 2 minutes he began to 

 lose the use of his limbs, and to stagger as the others had done. He was con- 

 vulsed more violently than any of the rest, and chiefly in the muscles of the 

 neck and spine. The muscles of his eyes were strongly convulsed, which ap- 

 pearance was not observed in the other dogs. He foamed at the mouth, yelled 

 frequently, and breathed with more difficulty than any of the rest. His con- 

 vulsions continued 20 minutes ; on their ceasing he lay quiet, as though he 

 slept, only that his eyes were open. His limbs were now grown perfectly 

 paralytic. 



We raised him up several times, and offered to set him on his legs, but he 

 did not attempt to use them. He continued in this way about 15 minutes 

 longer, and then was seized with another violent convulsion, which in 5 minutes 

 put an end to his life. 



On opening the abdomen, the veins of the stomach and guts were found very 

 much distended with blood, as in all the former instances. In the heart, lungs 

 and brain, there was no visible alteration. 



Exper. 6. — Oct. 30, Dr. M. injected 1^ oz. of the water, diluted with 3 oz. of 

 common water warmed, into the anus of a small bitch. Before he could untie her 

 she was seized with convulsions, and yelled much. She fell as soon as she was 

 loosed, and never after endeavoured to rise. She had convulsions, and great 

 difficulty of breathing about 2 minutes. She then lay still, with her limbs stiff 

 and extended, about 3 minutes ; during which time her lower jaw was con- 

 vulsed, and pulled alternately to and from the upper jaw, with a very quick 

 motion. 



After this her limbs became paralytic, and she gasped for breath about 2 

 minutes longer. She was quite dead in 7 or 8 minutes after the injection of the 

 clyster. 



In the abdomen, thorax and brain every thing appeared as usual. 



Exper. 7. — Nov. 2, Dr. M. injected o- oz. of the water, diluted with 3 oz. of 



