49O PHILOSOPHICAL TRANSACTIONS. [aNNO 1731. 



to its rump, then lay on its side and panted much : about 8 minutes after, he 

 gave it two tea-spoonfuls more, and it had fresh and strong convulsions, but 

 kept lying on its side, and thus stretching out its 4 legs one after another, draw- 

 ing in its flanks very quick ; in 15 minutes more it died ; being in all about an 

 hour from the first dose. 



An hour after it was dead, the Doctor opened it, and found all the contents 

 of the abdomen well ; the stomach was distended with wind, but empty of 

 milk, though full of froth, and a clear mucus of a much thicker consistence 

 than the liquor gastricus naturally is : they had no smell at all ; and the inside 

 of the stomach was not at all inflamed. 



On opening the thorax, he found the lungs a little redder than natural, with 

 some vessels on their outer membrane very turgid: on cutting them out a good 

 deal of clear red blood ran from them. The veins and both ventricles of the 

 heart were turgid, and full of coagulated blood, of a dark-brown colour, which 

 tinged his fingers of a dirty yellow, as if some gall had been mixed with it. 

 There was no blood in the arteries ; the foramen ovale was open. 



On opening the head, the dura mater appeared livid, as if bruised; its vessels 

 and the sinus falciformis were turgid, and full of the same blood, as the heart 

 and vessels near it. The cortical substance of the brain looked of an unusual 

 livid colour. 



Next day about 5 in the afternoon he took a large mastiff dog, weighing 

 75 lb. They tied him to a post as he stood on his legs, one holding him 

 strongly by the tail, he being very fierce and unmanageable. They injected 

 per anum 3 oz. of the second running; in 5 minutes he trembled and staggered 

 much ; would let them handle him ; he drew his hind legs after him ; tumbled 

 on his head ; panted and slabbered ; but gradually recovered so as to stand up, 

 though reeling and often sinking with his hind legs. Fifteen minutes after, 

 they injected 1 oz, more ; he immediately staggered and sunk behind ; soon 

 after he made water plentifully. They then led him to another kennel, where 

 he soon discharged the fa?ces plentifully, but of a hard consistence : the fasces 

 seemed moistened with the last injected oz. which Dr. M. imagined came away 

 by this stool ; he therefore immediately injected another oz. ; on which he 

 seemed more uneasy than before, tumbling on one side, and in about 10 

 minutes after, he fell fast asleep, breathing with difficulty ; ^ an hour after, 

 they roused him, found him slabbering, drowsy, sinking behind, and giddy : 

 about 1^ hour after the first injection, they found him as before; but provoking 

 him with a stick, he bit at it, and though naturally fierce, he was very quiet 

 when not struck : in a few minutes he reeled and fell a snoring again : about Q 

 at night he seemed very well, only drowsy. They left him all that night with- 



