6i6 



VHILOSOPHICAL TRANSACTIONS. [^ANNO 1733. 



experiment was made; and an account of this was afterwards published in the 

 Philos. Trans. 



Some Httle time before Christmas 1732, the small-pox appeared in this town, 

 chiefly of the confluent kind ; some had it with purple spots, and other violent 

 symptoms, of which several died. Towards the spring, the measles became 

 more epidemical, and also more fatal, than the small-pox. Some of the sub- 

 jects that had been visited but a little time before with the small-pox, and on 

 their recovery had their bodies purged, yet died of the violent cough which 

 attended and succeeded the measles, which afterwards seized them. The 

 measles continued to rage till almost all the subjects in this place were visited 

 with them, the small-pox continuing also during the whole time, yet making 

 but a slow progress, and to this time (August) it has not left us. 



About the end of February last, (1732) Mr. Francis Meyler inoculated his 

 own son, near 3 years of age, from a child of about the same age, who had 

 the distinct sort, but the pustules small. He made a slight incision on both 

 legs which took only in one; after 4 days a pustule appeared on the part 

 wounded, but did not much inflame it, nor make much progress. On the 7th 

 day the child grew feverish, and on the 8th, or towards the Qth day, instead of 

 the intended small-pox, the measles appeared all over his body, attended with 

 a cough; at which time the feverish disorder abated, till the 11th or 12th day; 

 he then became feverisii again, and towards the 1 4th day the small-pox appeared, 

 a small distinct sort, and few in number. After the eruption was full, he be- 

 came hearty; and so continued, not being visited with a second fever. After 

 this Mr. Meyler inoculated two other children from his own son, by applying 

 the matter, after a slight incision, to both the legs of each of them, but it did 

 not succeed. About the same time he inoculated two other children, a little 

 way out of town, from a neighbour's child, but neither of them were infected. 

 Its not succeeding he knows not what to impute to: whether to the slightness 

 of the incision, or to the want of a sufficiency of matter to infect with, or to 

 the want of a disposition in the subjects to be infected. 



About the latter end of March last, (1732) Mr. Richard Wright inoculated 

 a daughter of Tho. Kymer, Esq. of this town, between 3 and 4 years of age, 

 from another child of about the same age, who had the distinct kind. The 

 matter was applied to one of her arms, the incision being made pretty deep. 

 The inflammation began about the 4th or 5th day, and afterwards appeared 

 considerably great. She proceeded till the 7 th day in a very hearty and brisk, 

 state, at which time she became heavy, sick, and very feverish. Then an 

 eruption of the small-pox was expected; but her fever increased, and the next 

 day there were eruptions seejn all over her body, which proved to be the regular 



