LEUBE AND RIEGEL'S TEST-DINNER 



672 



LEUKOCYTIC 



Leube and Riegel's Test-dinner. A dinner to ascer- 

 tain the condition of the secretory function of the 

 stomach. It consists of 400 c.c. of beef-soup, 200 

 grams of beefsteak, 50 grams of white bread, and 200 

 c.c. of water. 



Leube's Pancreatic Meat-emulsion. See Alimenta- 

 tion, Rectal. 



Leuc-. For words thus spelled and not found below 

 see Leuk-. 



Leuca (leu' -kali). Synonym of Leprosy, q. v. 



Leucsethiops (lu-se' -the-ops) [Aevudg, white ; AlOiotp, 

 Ethiopian]. An albino of the black race. 



Leuce (lu'-se) \_aevkij ; Aewdc, white]. White leprosy ; 

 also morphcea alba. 



Leucemia (lu-se' -me-ah). See Leukemia. 



Leuchemia (lu-ke' -me-ah). See Leukemia. 



Leucin (lu'-sin) \_Aevk6q, white], C 6 H 13 N0 2 . A crys- 

 talline substance identical with amido-caproic acid, 

 occurring in the pancreas, spleen, thymus gland, and 

 other parts of the body. It is a product of pancre- 

 atic digestion. It may occur in the urine, especially 

 in acute yellow atrophy of the liver and in yellow 

 fever. In the impure form it crystallizes in rounded 

 fatty-looking lumps often aggregated and at times ex- 

 hibiting radiating striation. When pure, it forms very 

 thin, white, glittering, flat crystals, very soluble in hot 

 water, and oily to the touch. See Scherer's Test in 

 Tests, Table of. 



Leucinosis (Ju-sin-o' '-sis) [levudc, white]. I. Abnor- 

 mally excessive proportion or production of leucin, as 

 in the liver. 2. Acute yellow atrophy of the liver. 



Leucism, Leucismus (lu'-sizm, lu-siz'-mus) [Xewdc, 

 white]. In biology, whiteness resulting from bleach- 

 ing or etiolation ; albinism. 



Leucitis (lu-si'-tis). Same as Sclerotitis. 



Leuco- (lu'-ko-). For words not found under this form 

 see Leuko-. 



Leucomain (lu'-ko-mdn). See Leukomain. 



Leukangeitis (lu-kan-je-i' -tis). Synonym of Lym- 

 phangitis, q. v. 



Leukanilin (lu-kan'-il-in) \\evkoc, white ; anilin~\, C 20 - 

 H 21 N 3 . A substance obtained by digesting the 

 fuchsin salts with ammonium sulphid. It occurs as 

 a white, flocculent precipitate which separates from 

 water in small crystals. It yields rosanilin by oxidation. 



Leukasmus (lu-kaz'-mus). See Leukoderma. L., 

 Acquired. See Leukoderma. L., Congenital. See 

 Albinismus. 



Leukemia (lu-ke' -me-ah) [Aevudq, white; di/ua, blood]. 

 A disease of the blood and the blood-making 

 organs, characterized by a more or less permanent 

 increase in the number of white blood-corpuscles 

 and the marrow of bone, and by enlargement of the 

 spleen and the lymphatic glands, together or sepa- 

 rately. The etiology is obscure ; a history of malaria 

 or syphilis has been present in some of the cases. 

 The most characteristic symptom is the increase of white 

 corpuscles in the blood. Instead of the ordinary ratio 

 of white to red — 1 to 500-1000 — it may be 1 to 20, 1 to 

 IO, or even I to I. Interesting changes are seen in the 

 relation of the various forms of leukocytes established 

 by Ehrlich (see Leukocyte). In the myelo-splenic form 

 of" the disease, the lymphocytes are only slightly, if at 

 all, increased. The eosinophiles are present in much 

 larger numbers than normally. The polynuclear neu- 

 trophile forms are not increased. In addition to these, 

 cells not seen in normal blood are found — the myelo- 

 cytes, large mononuclear leukocytes, filled with neu- 

 trophile granules. They are held to originate in the 

 bone-marrow. There is a moderate oligocythemia and 

 a corresponding reduction in the amount of hemo- 

 globin. The liver and the kidney may be the seats of a 



diffuse lymphatic infiltration ; more rarely there are 

 distinct lymphatic tumors. Charcot- Leyden crystals 

 can be found in the blood after death. Fever, dizziness, 

 and hemorrhage, and a peculiar form of retinitis, ate 

 often present. The disease is usually fatal. 



Leukemic (lti-ke' -mik) \\evk6c, white ; a'ifia, blood]. 

 Pertaining to leukemia. 



Leuko- (lu'-ko-) \\evkoc, white]. A prefix signifying 

 white. 



Leukoblast (lu' -ko-blast) [aevk6c, white ; /?Zecrroc,germ]. 



1. The germ of a leukocyte ; also, a leukocyte itself. 



2. A cell in bone-marrow, of a type that is believed to 

 become developed into a red blood-corpuscle. 



Leukocarpous (lu-ko-kar'-pus) \_A£vk6q, white ; mp-6c, 

 fruit]. In biology, bearing white fruit. 



Leukochroos, or Leukochrus (lu-kok'-ro-os, lu-kok'- 

 rus) ['aevk6c, white ; jpwc, skin] . Having a white skin. 



Leukocotin, or Leukocotoin (lu-ko-ko'-lin, lu-ko-ko- 

 to f -in) [/.ewcoc, white ; coto\, C 21 H 20 O 6 . A body found 

 in coto-bark. 



Leukocrystallin (lu-ko-kris' -tal-in) \7xvn6q, white ; 

 upvoraXAog , clear ice]. Peculiar crystals occasionally 

 found in the blood of leukemic patients. 



Leukocyte (lu' -ko-sit) \Xevk6c, white ; Kvroq, cell]. 

 The colorless or white corpuscle of the blood. Leuko- 

 cytes have ameboid movement and are formed in the 

 lymphadenoid tissue of the spleen, lymphatic glands, 

 intestinal tract, bone-marrow, etc., and probably also in 

 the lymph and blood. Their average diameter is .01 

 mm. (yjfftf inch). In normal blood Ehrlich distin- 

 guishes the following varieties: 1. Lymphocytes — 

 small cells with a large nucleus that stains deeply, 

 and a small amount of protoplasm. 2. Large uninu- 

 clear leukocytes — large cells with a single large 



A. Lymphocyte. B. Large uninuclear leukocytes. C. Transi- 

 tional forms. D.Dd. Multinuclear forms— neutrophile cells. 

 E. Eosinophile cells. 



nucleus, staining less deeply, and a large amount of 

 protoplasm. 3. Transitional forms — cells with a single 

 indented nucleus. 4. Multinuclear cells, with neutro 

 phile granules — cells having a polymoqmous nucleus or 

 several nuclei. These constitute 70 per cent, of th 

 tire number of white blood-corpuscles. 5. Eosinophile 

 cells. In leukemia another cell, the myelocyte, makes it- 

 appearance. This is a large uninuclear cell, with neu 

 trophile granules. LSwit recognizes two cl 

 leukoblasts and erythroblasts, the latter the ant 

 ents of the red corpuscles. Most authorities reject 

 this division, however. L., Alpha, and L., Beta, 

 two terms used by Heyl, the former to express leuko 

 cytes that disintegrate during the coagulation oi the 

 blood ; the latter, those that do not. 



Leukocythemia (lu-ko-si-the' -me-ah) \^evk6c, white; 

 ki'toc, cell ; aijxa, blood]. See Leukemia, 



Leukocythemic (lu-ko-si-the' -mik) [aevk6c, white; 

 kitoc, cell; a"iua. blood]. Pertaining to leukemia 



Leukocytic (lu-ko-sit'-ik) [Aft»«Jc, white; kOtoc, cell]. 

 Relating to or characterized by leukocytes. 



