LUPIN I DIN 



many ot which are poisonous. A large number of the 

 species are American. 



.upinidin {lu-pin' -id-in) [lupus, a wolf], C 8 H 15 N. 

 A liquid alkaloid obtained from Lupinus luteus. 



.upinin Ui' -pin-in) [lupus, a wolf], C^H^N"./^. An 

 alkaloid, or tertiary amin, from the seeds of Lupinus 

 luteus; also, an alkaloid from the seeds of Lupinus 

 alius ; also, a glucosid from the leaves of both species. 

 All three are paralyzants, depressing the motor and 

 sensory centers. The one first named has been pro- 

 posed as a substitute for quinin. 



upinosis [lu-pin-o / -sis) [lupus, a wolf]. A disease of 

 cattle said by some to be produced by eating the herb- 

 age of certain poisonous species of lupine. See Lathy- 



upinotoxin {lu-pin-o-toks'-in) [lupinus, lupine; to^i- 

 I /aiv, poison]. A resinoid derived from certain poi- 

 ( sonous species of lupine, and said to be capable of 

 producing the symptoms of lupinosis. 

 upiology {lu-pe-ol' -o-je) [lupia, wen; 'fo^oc, science]. 

 The science of malignant tumors. 



upo:- [lupus, wolf; sldoc. like]. Having 



the nature ot lupus. 



upomania (lu-po-ma / -ne-ah) [lupus, wolf; pavia, 

 madness]. Rabies. 



upotome {lu f -po-tom) [lupus, wolf; rotti/, a cutting]. 

 A cutting or scarifying instrument sometimes used in 

 the treatment of lupus. 



upous {lu'-pus) [lupus, wolf). Affected with or per- 

 taining to lupus. 



jpulin ht'-pu-lin) [lupus, lupulus, hop]. I. C^H^- 

 r A crystalline principle obtainable from powdery 

 glands of the hop-plant. See Humulus. It is said 

 to be strongly narcotic. 2. The yellow, resinous 

 powder of hops, composed mainly of dried glands from 

 the strobiles of the plant ; it is the lupulinum of the U. 

 S. P. Its fluid extract and oleoresin are official. Dose 

 of the fld. ext. , gtt. 10-15 » OI " the oleoresin, gr. ij-v. 

 3. The precipitate from a tincture of the cones of hops, 

 Humulus lupulus, a nervine, hypnotic, febrifuge, an- 

 tiperiodic, and tonic. Dose from I to 2 grains. Unof. 

 jpulina {lu-pu-li'-nah) [L. : gen. , Lupulina\ Same 

 as Lupulin. 



Jpulinum [lu-pu-W -num) [L. : gen., Lupul/m"]. 

 Same as Lupulin. 



apulus lu'-pu-lus). See Humulus. 

 apus i/tt'-pus) [L., a wolf]. Lupus vulgaris; a 

 chronic disease of the skin and some mucous mem- 

 branes, characterized by the formation in the connective 

 tissue of nodules of granulation-tissue. It passes 

 through a number of clinical phases, and terminates by 

 ulceration or atrophy, with scar-formation. The cause 

 : of the disease is the tubercle-bacillus. L., Acne, an 

 i obstinate papular eruption of doubtful character occur- 

 ing in the localities usually selected by Acne vulgaris 

 landsometimes associated with it. L., Acneiform. See 

 i L. erythematosus sebaceus. L. anatomicus, the ana- 

 tomic tubercle. L., Cazenave's, lupus erythemato- 

 See also Diseases, Table of. L., Common, 

 • lgaris. L.. Disseminated Follicular, aden- 

 : a variety of acne confined to the face, espe- 

 cially in the situations usually occupied by acne. The 

 papules are from a large pin*s head to a pea in size, 

 conic and deep-red. They may coalesce to form a lupus- 

 ke tissue. L. disseminatus, a term applied to any 

 case of lupus with multiple patches. L. eczema, a 

 torm of L. erythematosus resembling eczema. L. 

 endemicus. See Aleppo Boil. L. erythematodes. 

 ^ynonym of Z. erythematosus. L. erythematosus, 

 L- trythematode s; Cazenave's lupus; a form not due 

 ■o the tubercle-bacillus. It occurs, as a rule, in mul- 

 tiple patches, with a tendency to symmetric arrange- 



709 LUPUS 



ment, chiefly about the face and head, occasionally on 

 the extremities, and rarely on the trunk. The patches 

 are sharply defined at the border, flat, very slightly 

 raised, and with a tendency to the formation of crusts. 

 The color is bright-red, and there are no nodules. 

 The disease tends to spread slowly at the periphery, and 

 new patches may form in the neighborhood of the 

 old. Feeble circulation favors the development of 

 the disease. It is most common in females of adult 

 or middle age. L. erythematosus aggregatus. 

 See L. erythematosus disseminatus. L. erythemato- 

 sus circumscriptus, the most common form, attack- 

 ing chiefly the head and face, especially the nose, 

 cheeks, and ears, often symmetrically. It appears in 

 the early stage as isolated or grouped, small, red spots, 

 about an eighth of an inch in diameter, with a yellow- 

 ish spot at the center, and a small, closely adherent scale. 

 These slowly extend peripherally and ultimately co- 

 alesce into patches of a dirty yellowish-white appear- 

 ance. Cicatrization occurs in the center. The disease 

 is one of long duration. L. erythematosus corneus, 

 L. erythematosus in which the scales are not greasy. L. 

 erythematosus discoides, the asymmetric form of 

 L erythematosus. L. erythematosus discretus, a 

 form of L. erythematosus in which irregular patches 

 are scattered over various parts of the body. It is 

 associated with constitutional symptoms — fever and 

 pains in the head, bones, joints, etc. L. erythema- 

 tosus disseminatus. L. erythematosus aggregatus; 

 Lupus-psoriasis ; a rare form of Lupus erythematosus, 

 characterized by a wider diffusion of the eruption, an 

 extension by repeated outbreaks, and by the fact that 

 the patches never coalesce. It is a chronic disease 

 usually, but maybe acute. L. erythematosus seba- 

 ceus, a form with special involvement of the seba- 

 ceous glands. L. erythematosus telangiectodes, a 

 variety characterized by marked dilatation of the cu- 

 taneous blood-vessels. L., Erythematous, lupus 

 erythematosus. L. exedens. Synonym of L. vul- 

 garis. L. exfoliativus. See Lupus maculosus. L. 

 exuberans, a form of lupus, usually Z. exulcerans, 

 associated with papillary excrescences. L. exulcer- 

 ans, a term used to distinguish that form in which 

 the destruction of tissue is rapid or intense, or in 

 which the epidermis is lost and a secreting ulcerating 

 surface is disclosed. L. frambcesiformis, L. fram- 

 bcesioides. See Z. exuberans. L., Fungous. 

 Synonym of Lupus exuberans. L. haemorrhagicus, 

 Z. erythematosus disseminatus associated with hem- 

 orrhagic vesicles and blebs that dry and form crusts. 

 L. hypertrophicus, that variety in which new con- 

 nective-tissue formation predominates over the destruc- 

 tive process, and markedly raised, thick patches result. 

 L. idiopatbicus. Synonym of Z. vulgaris. L. im- 

 petiginosus, a form of Z. erythematosus in its earlier 

 stages resembling impetiginous eczema. L. lymphat- 

 icus. See Lymphangioma circumscriptum. L. macu- 

 losus, a variety characterized by the eruption of very 

 soft, smooth, brownish-red, semi-translucent miliary 

 nodules, which develop in the connective tissue of 

 otherwise healthy skin without subjective sensa- 

 tions. This eruption constitutes the earliest sign 

 of lupus. When the surface desquamates, the 

 name Lupus exfoliativus is given to it. L. mili- 

 aris. See Z. , Acne. L. mutilans, lupus exe- 

 dens, causing destruction of tissue and disfigurement. 

 L.. Necrogenic, the anatomic tubercle. L. non-exe- 

 dens, lupus without ulceration. L. papillaris, L. 

 papi'lomatosus, a form characterized by papillary 

 growths thst may reach the size of the palm. These 

 are most frequently seen on the extremities and but- 

 tocks, and occur only on ulcerated surfaces. L. per- 



