GROUND 



283 



GUAIACOL 



ward and forward. G., Blessig's, the slight groove 

 in the embryonic eye that marks ©ff the fundus of the 

 optic cup from the zone that surrounds the periphery 

 of the lens and corresponds in position with the future 

 ora serrata. G., Carotid. See C, Cavernous (lllus. 

 Diet.). G.s, Developmental, fine depressed lines 

 in the enamel of teeth which mark the junction of the 

 primitive lobes. G., Dorsal, the medullary groove. 

 G., Harrison's. See under Harrison (lllus. Diet.). 

 G., Interventricular. See under Furrow (lllus. 

 Diet.). G., Mastoid, the digastric fossa. G., Mesio- 

 lingual, a developmental groove extending over the 

 juncture of the fifth cusp, on upper molars. G., Mus- 

 culospiral, one on the external aspect of the humerus 

 which lodges the musculospiral nerve and the superior 

 profunda vessels. G., Nasal. (See lllus. Diet. ) 2. 

 A furrow in the embryo leading from the mouth to the 

 nasal cavities. G., Nephric, one in the embryo in- 

 dicating the future nephric canal or segmental duct. 

 G., Neural, the medullary groove. G., Obturator, 

 the furrow at the superior and external border of the 

 obturator foramen lodging the subpubic vessels and 

 nerves when they emerge from the pelvic cavity. G., 

 Olfactory. See Olfactory Sulcus (lllus. Diet.). G., 

 Peroneal, one on the external aspect of the os calcis 

 lodging the tendon of the peroneus longus. G., Pos- 

 terolateral. See Fissure, Posterolateral (lllus. Diet.). 

 G., Primitive. See Primitive Streak (lllus. Diet.). 

 G., Pterygopalatal, G.. Pterygopalatine. I. One 

 in the ventral aspect of the pterygoid process of the 

 sphenoid. 2. A furrow on the vertical part of the 

 palate bone. G., Radial. See G., Musculospiral. 

 G., Scapular, the scapular notch. G., Schmorl's, 

 that resulting from emphysematous inflation of those 

 portions of the lungs which lie between the ribs. G., 

 Sibson's, a groove formed in some individuals by a 

 prominence of the lower border of the pectoralis major. 

 G., Sigmoid." See G., Cavernous (lllus. Diet.). G., 

 Spiral (of the humerus). See G., Musculospiral. G., 

 Sternal, one lying between the sternum and the pec- 

 toral muscles. G., Subcostal, a deep furrow lying 

 along the lower border and inner surface of a rib for 

 lodgment of the intercostal vessels and nerves. G. of 

 Sylvius, the sylvian fissure. G., Ventricular. See 

 Furrow, Interventricular (lllus. Diet.). G., Verga's 

 Lacrimal, a more or less pronounced groove extending 

 downward from the lower orifice of the nasal duct. 



Ground. (See lllus. Diet. ) G. -bundle, the principal 

 bundle of nerve-fibers in a group, as the ground-bundle 

 of the ventral and lateral columns of the spinal cord. 

 G.-b., Anterior, of Flechsig, that portion of the 

 anterior columns outside of the direct pyramidal tracts 

 and running throughout the entire length of the cord ; 

 they are made up of fibers having a short course. G.- 

 b., Posterior, of Flechsig, Burdach's column. 

 G.-itch. See Itch, Coolie. G.-water Theory. See 

 under Pettenkofer. 



iber's Test for hearing: If the end of the finger be 

 inserted into the ear after the sound of a vibrating 

 tuning-fork held before the ear has completely ceased, 

 md the tuning-fork be then firmly placed upon the 

 inger, a weakened sound becomes again audible and 

 remains so for some time. 



fochrome (grif-o-kroni) [ypv, a morsel; xpupa., 

 >lor]. Nissl's term for a somatochrome nerve-cell 

 the stainable portion of which consists of minute gran- 

 ges which tend to form threads or heaps, 

 hiacamphol ( gvmh-kam'-fol). See Guaiacamphol. 



Guacetin \ givas' -et-in). See Guaiacetin. 



Guachamacin / g;vah-skaw-mah'-kln ). Atoxic alka- 

 loid isolated by Schiffer from guachamaca. It is closely 

 allied to, if not identical with, curare. 



Guaconization (gwah-kon-i-za f -shun). Poisoning and 

 paralysis of the sensory nerve-centers from ingestion of 

 guaco, Aristolochia cymbifera, Mart. 



Guaethol {gu-eth'-ol). C 6 H 4 OC 2 H 5 OH. Guaiacol- 

 ethyl, an oily homolog of guaiacol. soluble in alcohol, 

 ether, or chloroform, insoluble in water or glycerin. It 

 resembles guaiacol in therapeutic action. Dose. o. I- 

 0.25 gm. Application, 15^ ointment. Syn., Ajacol; 

 Thanatol; Pyrocatechinmonoethyl ether. 



Guaiacamphol (gwi-ahkam'-fol). The camphoric 

 acid ester of guaiacol ; employed in treatment of night- 

 sweats of tuberculosis. Dose, 3-8 gr. (0.2-0.5 gm.). 



Guaiacene {gwi'-as-en). C 5 H g O. An oily crystalliz- 

 able liquid boiling at Il8° C, with odor of bitter 

 almonds, obtained by Deville (1843) from guaiac 

 resin by dry distillation. Syn., Tiglic aldehyd ; Gua- 

 jacen ; Guajol. 



Guaiacetin {gwi-as'-et-in). C 6 H 4 . OH . OCH 2 COOH. 

 Pyrocatechin monoacetate ; a white, odorless powder 

 or crystals soluble in water, melting at 131 C; ob- 

 tained from pyrocatechin by action of chloracetic acid. 

 It is used like guaiacol in tuberculosis. Dose, 7^4 gr. 

 (0.5 gm. ) 3 times daily and reduced in 3 weeks to 0.5 

 gm. daily. 



Guaiacocain ( g-ui-ah-ko-ka' -in). An anesthetic mix- 

 ture of cocain and guaiacol used in dentistry. 



Guaiacol. (See lllus. Diet.) Syn., Methylcatechol. 

 G. Benzoate. See Benzosol (lllus. Diet.). G.- 

 benzylester, C 6 H 4 (OCH 3 ) . OCH, . C 6 H 5 , occurring 

 in colorless crystals soluble in alcohol and ether; it is 

 used as a local anesthetic. Syn., Brenzcain ; Pyrocat- 

 echin methyl benzyl ether. G. Biniodid, C T H 5 I 2 2 , 

 reddish-brown powder with odor of iodin, soluble in 

 alcohol and oils; it is alterative and antituberculous. 

 Dose, 2 TT^ (o. 12 c.c. ) 3 times daily. G. Cacodylate, 

 a stable preparation occurring in white granules recom- 

 mended in tuberculosis. Dose, j^-2 gr. (0.032-0.13 

 gm. ). Syn., Cacodiacol ; Cacodyliacol. G., Cam- 

 phoric Acid Ester of. See Gitaiacamphol. G. 

 Carbonate, C, 5 5 H u , odorless, tasteless crystals, used 

 in tuberculosis. Dose, 3-8 gr. (0.2-0.52 gm.) 3 times 

 daily and gradually increased to 90 gr. (6 gm. ) daily. 

 Svn., Duotal. G. Cinnamate. See Stvracol (lllus. 

 Diet. ). G. Ethylenate, CH 3 . C 6 H 4 0' - C 2 H 4 - O . - 

 C 6 H 4 OCH 3 , a guaiacol ethylene ester, forming yellow 

 needles slowly soluble in water. It is used in tuber- 

 culosis. Dose, 8-15 gr. (0.5-1 gm. ) twice daily. 

 Syn., Ethylene-guaiacol. G. -methylene. Acetylized. 

 See Eugoform. G. 01eate,a reaction-product of oleic 

 acid, guaiacol, and phosphorus trichlorid, misciblewith 

 fatty oils, ether, benzene, or chloroform ; soluble in 

 alcohol. It is antiseptic and antituberculous. Dose, 

 5-10^(0.3-0.6 c.c. ) 3 times daily in capsules. Syn., 

 Oleoguaiacol. G.-phosphal. G. Phosphite, P. (C 8 - 

 C 4 .OCH 3 -0) 3 , occurring in white needles melting at 

 775° C. It is used in tuberculosis. Dose, 15-30 gr. 

 (1.0-2.0 gm.) daily. G. Phosphate, (C 6 H 4 OC- 

 H 3 ) 2 P0 3 , obtained from guaiacol dissolved in soda 

 solution with addition of phosphorus oxychlorid, oc- 

 curring in colorless, hard tablets, soluble in toluene and 

 acetone, melting at 98 C. Used in fever of tubercu- 

 losis. Dose, 4 gr. (0.25 gm. ) every 3 or 4 hours. G. 

 Salicylate, G.-salol, C 14 H 12 4 , white insipid crystals 

 with odor of salol, soluble in alcohol, and melting at 

 about 65 C. It is an intestinal antiseptic and is em- 

 ployed in phthisis, dysentery, rheumatism, etc. Dose, 

 15 gr. several times daily. Max. dose, 150 gr. per day. 

 G. Succinate, (C 8 H 4 OCH 3 \C 4 H 4 4 , obtained from a 

 mixture of guaiacol and succinic acid with phosphorus 

 oxychlorid ; fine needles soluble in acetone and toluene, 

 melting at 136 C. Dose, 2 Tr^ (o. 12 c.c.) 3 times 

 daily in tuberculosis. G. Valerate, G. Valerianate, 



