CARDIOVASCULAR CHANGES DURING CEREBRAL ANEMIA 



33 



Effect of repeated occlusions in cats deprived of adrenal glands. The 

 procedure of repeated occlusion in the same animal was undertaken in 

 a final series (six cats) in which both adrenal glands were ligated. In 

 each of these animals one control occlusion was made, then by means 

 of dissection through the latissimus dorsi (double incision from the 

 back) the adrenals were isolated and secured by ligatures. No signifi- 

 cant fall of pressure was obtained immediately on ligation of the ad- 

 renals, thus confirming the observation of Hoskins and McClure (102) 

 and Young and Lehman (103). Following this, the procedure was 



Fig. 5 A: Control curve of 3 minute occlusion. Ligation of the head arteries 

 in the intact and fresh animal. Initial rise is followed by a depression level 

 coming cogether with a slowing of the heart. High level of pressure maintained 

 throughout the response. 



B. Cat 48: Repeated cerebral anemia; stellate ganglia excised; 14th successive 

 occlusion. Dissociation of two peaks very well marked. Level of pressure 

 between occlusions extremely low (20 mm. Hg. above base line). 



C. Cat 53: Repeated cerebral anemia; adrenal glands ligated; 7th successive 

 occlusion, obtained just before collapse. Drum revolving at same rate as above. 

 Time of this reaction, 2 minutes. Control reaction in this animal, when fresh 

 and intact had occupied 3| minutes. Abruptness of initial rise and final fall 

 characteristic of records after ligation of the adrenals. 



THE AMERICAN JOURNAL OF PHYSIOLOGY, VOL. 60, NO. 1 



