378 ULCERATION OF PEYER'S PATCHES IN CONTINUED FEVER. 



In regard to the history of this department of the morbid 

 anatomy of fever, I may state that Dr. Bright has given very 

 beautiful representations of the sloughs and ulcers in his 

 Reports of Medical Cases. Louis and Chomel have referred 

 to the appearance of the matter which distends the glands, 

 and compared the process to the tuberculous. Schonlein, in 

 his General P.athology, has made a general allusion to the de- 

 posit, and to the changes which occur in the patches.* Gruby, 

 in a work on the Microscopic Character of Morbid Products,"^ 

 was the first, as far as I can learn, who figured and described 

 the cells of which the deposit consists. Finally, KokitanskyJ 

 has generalised the subject, and considered the matter de- 

 posited as peculiar to typhus fever, and referable to the same 

 category as cancer, tubercle, etc. 



My own observations have been made without reference 

 to any hypothesis as to the pathology of fever. 



* Schonlein, Allgemeine und specielle Pathologic und Therapie, Zweiten 

 Thiele, 1839, p. 23. 



t Obs&rvationes Microscopicce auctore Dav. Gruby, 1840, p. 44. 



J Rokitansky, Handbuch der Patlwlogischen Anatomic, band iii. p. 265. 



