STUDIES IN GENERAL PHYSIOLOGY 



a larger number of organic acids, especially of the fatty series, 

 which I wish to report here. It is clear that these apparent 

 exceptions to the theory of electrolytic dissociation in the 

 case of the organic acids must yield material for understand- 

 ing the chemical changes which go on in living matter. 



The experiments were made as the previous ones. Five 

 or 10 c.c. of a one-tenth normal solution of the acids were 

 added to 100 c.c. of a NaCl solution. The gastrocnemius of 

 a frog was introduced into such a solution and its increase 

 in weight determined at certain intervals. 



The solutions which contained 10 c.c. of a one-tenth nor- 

 mal acid in 100 c.c. of a 0.7 per cent. NaCl solution in 

 which therefore the concentration V equaled 110 gave more 

 constant results than those solutions in which V equaled 210. 

 The following table gives the results of several series of 

 experiments with a series of acids when V equaled 110. The 

 Arabic figures give the increase in weight which each muscle 

 showed, expressed in per cent, of its original weight after 

 remaining for one hour in the solution. 



( F=110) 



We will now compare with this series the degree of dis- 

 sociation of these acids when V= HO. 1 



1 Calculated according to OSTWALD, " Ueber die Affinitatsgrossen organischer 

 Sfturen," Abhandlungen der Sdchsischen Gesellschaft der Wissenschaften, Vol. XV, 

 p. 89. 



