482 PHILOSOPHICAL TKANSACTIONS. [aNNO 1741. 



the spitting was very little increased, and as tough as ever : nor did the fistulous 

 ulcers seem in the least disposed to heal up, but vented a vast deal of stinking, 

 oily, sanious matter ; and even new ones broke out under each axilla, and a 

 very large phyma rose on the coccyx, which soon discharged the same kind of 

 virulent matter ; though we found the bone, and even the periosteum, quite 

 sound and untouched. 



The scales were now grown so hard and stiff, that he could scarcely bend a 

 limb, or finger : also, abundance of ulcers, from whence flowed great quanti- 

 ties of greasy, purulent, and somewhat bloody matter, were broke out in his 

 thighs and buttocks. A very large tumour was also risen in his right breast, 

 and soon after on the left, voiding prodigious quantities of the same kind of 

 matter. 



It was observable, that wherever any of these ulcers appeared, they ran only 

 under the skin, being entirely seated in, and feeding on, the membrana adiposa ; 

 so that the muscles and tendons underneath appeared as fair and florid as in the 

 most healthy constitution. 



Dr. H. now unfortunately found, though too late, there was nothing to be 

 done by mercury in any form ; and therefore determined to run it oflT, and try 

 the guaiacum method and sweating, so much recommended of old, and in some 

 cases so justly, by Sir Ulric Hutten, and others ; at the same time keeping up 

 a most plentiful dilution, attempting withal to detach the scaly cuticle by con- 

 tinued emollient baths, which at the same time also would partly act by dilution. 

 By this means the scales came off apace, just in the manner usual in the con- 

 fluent small-pox ; only the exuviae were here much larger, several being above 

 4 or 5 inches over. In about a week's time, this coat of mail was pretty well 

 cleared off, and his breath, from the most horribly nauseous he ever smelt, be- 

 came as sweet as that of an infant. Nor was the matter spit, though still very 

 viscid, any way fetid : for the mercury was pretty well run down by lenient 

 cathartics, and the sloughs of his mouth cast off. 



He was now become exceedingly emaciated : wherefore he ordered him 

 plentiful liquid nourishment with vipers, and large dilution, avoiding every 

 thing that was in the least gross or fatty. But with all this he still kept to his 

 three pints of strong decoction of guaiacum every 24 hours, sweating at least 

 2 or 3 of them. 



Under this method Dr. H, conceived some hopes of his recovery, as he 

 seemed now to gain some small degree of strength and spirit ; but still his 

 ulcers rather increased than abated, and continually discharged a vast quantity 

 of matter, though by no means so thick, putrid, or bloody; and, indeed, in a 

 most profuse manner from under each axilla. 



fl 



