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VOL. XLIII.] PHILOSOPHICAL TRANSACTIONS. 17 



the 26th of July when the rash was still upon him, after heating himself with 

 walking, he became suddenly chilled. In the evening of that day he was seized 

 with a shivering, followed by vomiting and some degree of feverish heat. The 

 next day he was rather better; but on the 3d day the fever returned with vomiting 

 and head-ach. The rash had disappeared, and a vomiting of a chocolate coloured 

 matter, with bilious evacuations by stool, &c. showed an aggravation of the dis- 

 order. The next day the pulse was small and frequent, the patient complained 

 of pain about the left orifice of the stomach, and the vomiting was more urgent. 

 In the morning of the 5 th day the stools were discovered to be bloody, and in the 

 course of the day blood was also discharged by vomiting, and in large quantities 

 both ways, black and coagulated, though what had come away by stool in the 

 morning was florid. A consultation was held, at which it was determined to have 

 recourse to v. s. the Peruvian bark, (which had been given before) and certain 

 astringent and cordial medicines. After v. s. the patient became manifestly 

 weaker; delirium and a train of alarming symptoms succeeded, and he died on 

 the 6th day from the first attack, and the 3d day from his taking to his bed. The 

 quantity of blood discharged amounted in the whole to nearly 8 lb. 



Eighteen hours after death, the body was opened. The lungs were found to be 

 of a very dark colour, and in a diseased state. The heart appeared flaccid, and 

 the foramen ovale was found open. The convex part of the diaphragm was in- 

 flamed, and its concave part, where it is in contact with the stomach, appeared 

 black, and its vessels were turgid. 



In the abdomen, the liver appeared nearly of its natural colour in its convex 

 part, but in the concave part, where it is contiguous to the stomach, it was of a 

 dark and black colour. On cutting into its substance, it was found to be inter- 

 nally of a pale colour, and almost destitute of blood. The substance of the 

 spleen was found black and quite corrupted. The kidneys, mesentery, and other 

 parts, were almost destitute of blood. The whole lining of the oesophagus was 

 beset with coagulated blood. The stomach was distended and inflamed. It con- 

 tained a large quantity of watery fluid, mixed with black fetid blood. The blood- 

 vessels of the stomach were turgid with blood. At the bottom of the stomach, 

 about 4 fingers breadth from the pylorus, they were astonished to find a large 

 round tumour, which weighed nearly 5 oz. In the upper part of this tumour 

 there was a round hole, about 4- an inch in diameter.* Externally this tumour was 

 of a dark red colour; it was of a sarcomatous substance, and of a cancerous 

 nature. The whole tract of the intestinal canal was externally red, and the 

 small intestines were in a gangrenous state. From the pylorus along the whole 

 tract of the duodenum there was found a great quantity of dark coloured coagu- 



* The aforesaid orifice was found to lead into sinuses^ which contained some ichor. 

 VOL. IX. D 



