VOL. XLVII.] PHILOSOPHICAL TRANSACTIONS. 2^9 



induced by friction would dilate the mouths of the absorbent vessels, and draw a 

 moderate flux of juices to the part, so that they might take in a sufficient quantity 

 of variolous matter to bring on the disorder,* 



LXXVIl. A Sequel of the Case of Horace JValpole, Esq. relating to the Stone, 

 since his first Account in April, 1750.-|* p. 472. 



After having found himself for 1 years together perfectly well, and free from 

 all symptoms of his former disorder, having taken for some time no more than 

 one half of the quantity of soap and lime-water that he had before used; in 

 November 1750, Mr. W. came out of the country in his coach in the usual 

 travelling pace, without the least inconvenience. But having ventured some- 

 times to go in a coach, after he came to town, on the stones, he began at times 

 to feel the symptoms of the same disorder, which on any motion, besides that of 

 going in a chair, even in walking to any degree, increased on him ; and driving 

 only in his chariot through the two parks to Kensington, without going on the 

 stones, he found himself greatly affected, by making frequently and involuntarily 

 water, and sometimes bloody, accompanied with sudden stops, and severe pains. 

 However, taking the precaution of going by water as far as the Old Swan, and 

 being carried from thence in a chair as far as Whitechapel, he ventured in a 

 chariot, fitted up with the best French springs, to go into the country with Mrs. 

 Walpole about midsummer last; but before he had got half way to Epping, 

 though the horses went but a gentle pace, he felt as great uneasiness, attended 

 with the same severe symptoms, as he had ever done; which frequently returned, 

 and continued during the whole journey for 4 days together, with little or no 

 abatement, except while in bed ; whereas formerly, after he had lain some time, 

 he was perfectly easy the whole night. In alighting from the coach, on his ar- 

 rival at his house in the country, he had indeed a cruel fit; but after he had 

 rested one night, and kept himself as quiet as possible for several days, he found 

 himself perfectly well again; and as he never went in a coach, and did not walk 

 much, during his whole stay in the country last year for about 5 months together, 

 he never felt the least symptom of uneasiness. 



A few days before leaving the country in November last, he took a turn or 

 two round his park in the chariot, free from pain; which encouraged him to 

 undertake a journey to town again in the chariot, by short stages, and gentle 

 driving: and it was performed in 5 days to Whitechapel, without his being sen- 

 sible of the least inconvenience any part of the way ; neither had he felt any since 



• After the above account was communicated to the Royal Society by Mr. Brooke, the experiment 

 was tried on 4 children by Dr. Conyers at the Foundling Hospitalj but was followed neither by the 

 variolous fever nor eruption in any one of the instances.— Orig. 



■\ See p. 135 of this vol. of these Abridgments. 



