VOL. XLVIT.] PHILOSOPHICAL TRANSACTIONS. 2Qg 



Some time after this 2 waggoners were run over by a waggon loaded with 

 stone, and each of them had one leg broken in a miserable manner. These 2 

 men being brouglit to the Hospital of the Charity, Mons. F. saw no other hopes 

 of success but in amputating the legs ; and therefore he requested Mr. Brossard 

 would be present, and give a proof of this new application, which they applied in 

 the following manner : As soon as the leg was cut oft', he slackened the tourne- 

 quet, to discover the vessels ; and Mr. Brossard applied, on the orifices of the 

 2 arteries, 2 pieces of his astringent, fastened one on the other with a ribband. 

 After tlie application was made, Mr. F. straitened the tournequet, and passed 

 the 2 ends of the ribband, which was fastened to the upper piece of the astringent, 

 on the stump over the knee, and applied a linen bag, filled slightly with the 

 same astringent in powder, on the whole wound ; and over all applied the com- 

 mon dressings in the like case. After the dressing was finished, he slackened 

 the tournequet, and 2 hours after took it entirely away. Eight and forty hours 

 after this, they took oft' the dressings, and not the least drop of blood followed 

 from the vessels: and they again applied 1 single piece of the astringent on the 2 

 vessels ; and he dressed the other parts of the wound with pledgets of lint, with 

 common digestive, a styrax plaster, and the usual bandage. 



The 3d day the astringent fell off" of itself in the time of dressing ; and the 

 patient, after that time, was dressed in the common manner. The same was done 

 to the other patient, after the amputation, as to this. 



The first of these men died on the 5 th day, and the other on the Qth : but 

 there did not appear, through the whole, the least tendency to an haemorrhage. 

 Thus the remedy fairly produced its effects, as to the stopping the blood. 



However, in order to determine the manner in which this astringent produces 

 its effects, he examined the blood-vessels of those 2 patients after their death, 

 and found them contracted and straitened, as if they had been tied, and in the 

 largest of them a conical coagulation of the blood, which was an inch and half 

 long : and after having taken out this coagulation, it was with difficulty that 

 he could introduce the point of a very small probe into the orifice of that vessel. 

 The patient, who died on the Qth day, had the arteries contracted in the same 

 manner ; but with this difference, that the coagulation was at least 4 inches long. 



Mr. Morand has employed this remedy with success in applying it to a wound, 

 made by a sword in the bending of the arm : and Mr. F. himself had made use 

 of it, with great success, on occasions where the temporal and intercostal 

 arteries had been opened. In the last-mentioned cases, he applied only 1 piece 

 of the styptic on the opening of the artery; and this generally fell off^ at the lirst 

 dressing, that is, 48 hours after the application, without th'.i least appearance of 

 an hicmorrhage, or other ill symptoms, which could raise any objection to this 

 styptic i for those patients were all recovered. 



aa2 



