548 PHILOSOPHICAL TilANSACTlONS. [aNNO 1754. 



and made a strong compression at the end of the stump, on which the bleeding 

 ahnost intantly abated, which was totally stopped in about half an hour after; 

 and, in the whole, he believed he did not lose more than 12 oz. of blood. Now, 

 apprehending that the circular structure of the common bandage, as usually 

 applied, might produce the same inconvenience, which he observed arose from 

 the tourniquet-ligature before it was quite loose, if no other attended it, having 

 strong suspicions of tight bandage doing much mischief, he therefore only put 

 several strips of common plaster, about an inch broad, over the piece cf stiff 

 paper at the end of the stump, to meet and lap over at the top of the knee 

 when bent, and then slipped on a barber's woollen cap; which method seemed 

 to answer the purpose very well in this, as he had found it do in some other 

 amputations. A physician, and 4 surgeons of eminence, who were desirous of 

 seeing the effect of the agaric, were present at the operation. Four days after 

 he opened the stump, but took, away no more of the dressings than what were 

 loosej among which were '2 or 3 pieces of the agaric, without any signs of fresh 

 bleeding, or visible pulsation at the ends of the arteries. Two days after he 

 dressed it again; the stump then appeared well digested all over, and had a much 

 better aspect than could reasonably be expected in such an unpromising subject; 

 and appearances were so favourable as to give hopes -of his recovery, though he 

 was not without distant fears, which he was guarding against as much as possible. 



C Extract of a Letter from Mons. Bonnet, F. R. S. of Geneva, to John Cle- 

 phane, M. D., F. R. S. Translated from the French. Dated Geneva, June 3, 

 1754. p.818. 



The inoculation of the small-pox continues to be attended with the greatest 

 success in our city. Of 70, who were inoculated, there was not one in any 

 danger. Lausanne has been as it were forced to imitate us; and we hope, that 

 this excellent method, which we received from England, will spread itself from 

 one place to another, for the good of mankind. Mons. de la Condamine has 

 read to the Royal Academy of Sciences at Paris a dissertation on this subject, 

 which was greatly applauded. But I presume, that the French will be a long 

 time in adopting the practice of inoculation. The clergy there throw a terrible 

 obstacle in its way. 



CI. Extract of a Letter from Constantinople, of the iQth September, 1754, 

 from Murd. Mackenzie, M. D. concerning the late Earthquake there, p. 81 9. 



On the 2d instant we had a terrible shock of an earthquake, about ^ after 9 

 at night, which moved from east to west, and has done a great deal of mischief 

 here, and in the neighbourhood. I shall only mention what I have seen. 



Four of the 7 towers are much hurt ; one of them, which is an octagon, has 



