VOL. L.] PHILOSOPHICAL TRANSACTIONS. 209 



never had the least symptom of a 2d infection. Mr. Bewley, a surgeon of re- 

 putation in Lincolnshire, inoculated 3 beasts 2 years old, for Mr. Wigglesworth 

 of Manton, in the dew-lap, and with mucus from the nostrils. All 3 had the 

 regular symptoms of the contagious distemper in a mild manner, recovered, and 

 though they herded a 1 2 month after with 5 or 6 distempered beasts, they never 

 were the least affected. Mr. Bewley also declared to Mr. Thorpe, that there 

 never was one instance produced that he knew of, of a 2d infection. 



Since it was plain, that notwithstanding neither well-digested pus was made 

 use of, nor incisions made in the properest places, and it might be supposed few 

 medicines were given ; yet inoculation succeeded so as to bring on the distemper 

 in a regular and mild manner, as ".ppeared by the cows with calf not slipping 

 their calves ; one might fairly conclude, that in this contagious distemper, like 

 the small-pox, the practice of inoculation was not only warrantable but much to 

 be recommended. 



But how came it then, that neither by application, digestion, nor inoculation, 

 the distemper was not communicated in France ? The Marquis says, that this 

 distemper was not communicated but from one beast to another immediately. 

 Dr. L. begged leave to say, that to his knowledge the distemper in February 

 17 56 was carried from the farm yard, where he visited some distempered cattle, to 

 2 other farm yards, each at a considerable distance, without any communication of 

 the cattle with each other, and merely by the means of servants going to and 

 fro, or of dogs. The experiments made on 4 beasts, by tying over their heads 

 part of distempered hides, or pieces of linen and woollen cloth or silk, which 

 had received the breath and steams of dying cattle, serve to show, by tiie bul- 

 lock's forcing off the cloth tied about him, that the putrid stench was dis- 

 agreeable to him ; but that neither his blood nor that of the other 3 beasts, was 

 then in a state to receive the infection. 



With regard to the pustules, which the Marquis relates were mixed with oats 

 and bran, or dissolved in white wine ; the distempered bile, which was mixed 

 with milk ; milk taken from diseased cows ; water, in which part of a distem- 

 pered hide had been steeped ; and the precaution taken to force these mixtures 

 into the paunch of calves by means of a funnel, whose end was covered with a 

 piece of raw distempered skin, that the beast might both swallow and suck in 

 the disease ; all these experiments could have no other effect than what fol- 

 lowed ; which was, that the acrimony of the distempered bile created first a 

 nausea, and then produced a violent scouring, which killed the beast, leaving 

 marks of its irritation on the intestines. 



The practice of inoculation was but lately followed, and even now but little 

 known in the provinces of France. Its advantages had not long since been 

 strangely disputed at Paris. In the case of inoculating cattle, instead of a slip of 



VOL. XI. E £ 



