3^6 PHILOSOPHICAL TRANSACTIONS. [aNNO 1759. 



that time he felt an unusual pain in his right wrist, which in August 1757 be- 

 gan to swell : this obliged him to cease from his usual labour. In the space of 

 a month more, this swelling became a hardness, like a bony substance ; and 

 continually shooting on, in Dec. reached up as far as the elbow ; all the mus- 

 cles continually growing into a bony substance, and dilating so, that his wrist 

 and arm were twice as thick and broad as in the beginning. About a week 

 after the pain began in his right wrist, he was seized with the like pain and 

 swelling in the left wrist. This had proceeded in all respects in the same man- 

 ner as in his right arm. The whole substance of each arm, from the elbow 

 down to the wrists, felt as if it were one solid bone. The ossification was 

 shooting downwards into the fingers, and upwards into the elbows ; so as to 

 prevent the bending of the lingers or elbow of the left arm. It had likewise shot 

 upwards, so as to seize the great muscles of each arm between the elbows and 

 shoulders. The continual pain and dilatation of the arms occasioned a burst- 

 ing of the skin and fleshy parts about each elbow in Nov. 1758 ; out of which 

 oozed a thin yellowish humour, with a little digested pus. Some of these 

 breaches healed up of themselves. One small orifice in each elbow then conti- 

 nued to run. 



In March 1758, he was seized with the like pain and swelling in his right 

 ancle, whence such another bony substance soon grew as in his arms. This 

 bony substance shot up from his ancle, both in the inward and outward side 

 of the right leg, half way up to the knee ; and the like bony substance in the 

 inward side, shot downward from the pan of the knee 8 inches along the shin- 

 bone and was daily increasing ; so that he walked with much pain and dif- 

 ficulty, and after resting in his walk, grew very lame. This person was of a 

 very thin habit of body, and in size 5 feet Q inches ; somewhat inclined to an 

 hectic, though he had no cough. 



XV. A further Account of the same Case, By the Rev. kVilliam Henry, D. D., 

 F.R.S. Dated Dublin, May 24th, 1759. 



In this letter Dr. H. states, that he had sent Wm. Carey up in March pre- 

 ceding, to Mercer's hospital in Dublin ; that after examining his case, the phy- 

 sicians and surgeons concluded, that the only probable chance to prevent the 

 progress of the ossification, and to remove the evil already effected, was putting 

 him into a mercurial course. This they tried ; and after some slighter mercu- 

 rial medicines, they, in the latter end of April, laid him down in a salivation, 

 through which he passed with safety. This dried up the running sores at his 

 elbows, occasioned by the bursting of the skin, through the Ossification. Some 

 lighter callus, which was shooting into the bones, seemed to be softened : in 

 consequence of which he could move his elbows, and the joints of his fingers, with 



