60 THE BIOLOGY OF DAILY LIFE. 



lymphatic glands, and with diseases of the 

 medulla of bone. 



" HISTORY. Pallor of the blood, as if pus 

 were mixed with it, was noted by Bechat in 

 the beginning of this century ; and the com- 

 bination of this appearance, with enlargement 

 of the spleen, was observed by Velpeau in 

 1827. The dependence of this alteration in 

 the blood on an excess of pale corpuscles was 

 described by Donnd in 1844, and interpreted* 

 by him as due to imperfect transformation of 

 white into red corpuscles. 



"In 1845 two cases of this disease were 

 published together, the one by Dr. Craigie, 

 the other by Dr. Hughes Bennett; and 

 to the latter appears to belong the credit 

 of recognising the salient features of the 

 affection as a distinct malady. A month later, 

 however, Virchow published another case, 

 independently and admirably worked out.f 



" In all these cases the changes in the blood 

 were only recognised after death. 



" It was first observed during life in 1846 

 by Dr. H. W. Fuller, and subsequently by Dr. 

 Walshe. In Germany the first case was 

 diagnosed during life by Vogel, 1848. Since 

 then numerous cases and descriptions of the 



* How often are observations correct, while the interpretation is 

 faulty ! 



t There is ambiguity about this sentence, but we thinkit means 

 not that the patient was either (1) worked out of life, or (2) 

 worked into health, the latter alternative is scarcely possible, 

 but simply that the description of the disease was admirable. 



