CONTENTS 



PAGE 



INTRODUCTION > > >: ;. xiii 



THE METHOD 



CHAPTER I 

 HISTORICAL 1 



Therapy of typhoid fever by Fraenkel and Rumpf Specificity of Tuberculin 

 Fixation abscess of Fochier Nucleic acid Colloidal metals Auto- 

 serotherapy Tumor treatment Leukocytic extracts Paraspecific 

 therapy of Paton Deutschmann serum Schafer vaccine Intravenous 

 gonoc v occus vaccine Intravenous typhoid vaccine in typhoid fever 

 Heterobacterio-therapy of Renaud and Kraus Protein split products 

 Milk Recognition of the nonspecific factor in therapy. 



CHAPTER II 

 THE NONSPECIFIC AGENTS 12 



Counterirritation: Cautery, Seton, Fontanelle, Blisters, Rubifacients 

 Serums: Normal, human, horse, sheep, beef, goat, chicken serum, etc. 

 Immune Serums: Human convalescent serum Antimeningitis, anti- 

 dysentery and antistreptococcus serum Diphtheria and tetanus anti- 

 toxin Antiyeast serum (Deutschmann serum) Antituberculosis serum 

 (Marmorek, Maragliano, etc.) Related Agents: Plasma-serum of 

 Richet Blister serum Pleural fluid Cerebrospinal fluidJoint fluid 

 Proteins: Egg and seralbumin Milk Fat-free milk Casein Gelatin- 

 Plant proteins Nucleo-proteins Nucleo-hexyl Protein Split Products: 

 Proteoses (Albumoses) Deuteroalbumose Globin Histamine Witte 

 Peptone Enzymes : Trypsin Amylopsin Leukoprotease (Leukocytic 

 Extract) Tissue Extracts: Tumor extracts and autolysates Cartilage 

 and other tissue extracts (Heilner) Organotherapy Vaccines: Typhoid 

 Dysentery Colon Cholera Meningococcus Gonococcus Staphylo- 

 coccus Streptococcus Pyocyaneus Pneumococcus Influenza and 

 diphtheroid vaccines Mixed vaccines Vaccinurin, Danysz vaccine and 

 Much's antigen Bacterial Extracts and Related Substances: Tubercu- 

 lins! Typhin Coley's fluid Phylacogens Bacterial autolysates Col- 

 loidal Metals: Gold Silver Platinum Mercury Sulphur lodin 

 Zinc Iron Antimony Manganese-^-Copper, etc. Miscellaneous: Dis- 

 tilled water Hyper- and hypptonic salt solution Sugar solutions 

 Formalin Solusin Hetol lodidea Turpentine Yeast Irradiation 

 Sunlight Roentgen rays Radium rays, etc. Biological alterations- 

 Depression immunity. 



CHAPTER III 

 THE NONSPECIFIC REACTION ...... 46 



Chill Temperature Pulse rate Blood pressure Sweating Nausea and 

 vomiting Splenic enlargement Effect on menstruation Nervous ir- 

 ritability Herpes and urticaria headache Delirium glandular activity 

 Nitrogen balance Effect on weight curve Renal effects Permea- 



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