192 PROTEIN THERAPY 



ous times, namely, that intravenous injections of this kind may be 

 followed by a very marked reaction on the part of the patient, so 

 that even relatively small doses may incite a severe general reaction. 

 Holler treated 32 cases of erysipelas with small daily injections of 

 deutero-albumose, all of whom made a prompt and uncomplicated re- 

 covery. The reaction was, however, at times quite severe, in some 

 cases the patients becoming delirious for a short period following the 

 chill. Nolf has described the use of peptones, Kraus, Turnheim 

 and Reichenstein obtained satisfactory results with milk injections 

 while Blumenau treated 77 cases with nuclein injections. In this 

 series the favorable effect was more apparent in the general condi- 

 tion of the patient than on the local process. Audain and Masmon- 

 teil used sugar solutions; Englander reports that following the intra- 

 venous injection of salt solution 100 to 150 c.c. the temperature 

 usually returned to normal very promptly; v. Szily and Schiller used 

 typhoid vaccine successfully. A number of observers have obtained 

 satisfactory results with either direct or artificial sunlight. (Bruce 

 and Hodgson, Capelle, Klapp, etc.) 



Schmidt has recently reported on a series of 52 cases treated with 

 milk injections. Of these 44 involved the face, 4 the upper extremi- 

 ties, 3 the lower and in one case the abdominal skin was involved. 



The results were as follows: 



Upper Lower 



Defervescence Face Cases Extremity Abdomen 



1st Day after injection .... 27 2 1 1 



2nd " " " 8 2 2 



3rd " " " .... 4 



Of the 4 cases that did not respond until the 3rd day, one had an angina, 

 and two had a lymphadenitis colli (tuberculous). 



The five remaining cases which persisted longer than 3 days were all 

 complicated by other infections. 



INFLUENZA 



The recent pandemic of influenza gave opportunity to study the 

 effect of a great variety of nonspecific agents on the clinical course, 

 particularly of the complicating bronchopneumonia, and a considerable 

 literature has developed which can only be briefly reviewed at this 

 time. 



Colloidal Metals. Teller reported satisfactory results with col- 

 largol. Capitan, who treated 321 cases of uncomplicated influenza 

 and 208 cases of bronchopneumonia of influenzal origin, used a col- 

 loidal arsenic preparation, which he had previously found useful in 

 tuberculosis and syphilis. The preparation contained 3 mg. of arsenic 

 and 2 mg. of silver per cubic centimeter, and of this from 6 to 9 

 c.c. were injected either intramuscularly or intravenously. He de- 



