196 PROTEIN THERAPY 



Neuralgias persisted for some time after the temperature had returned 

 to normal. Voorthius claims to have found the fixation abscess useful 

 in encephalitis. 



MEASLES 



Both Holler and Miiller have treated cases with albumose and 

 with milk injections. Pehu and Pillon report that injections of tur- 

 pentine were very satisfactory. 



PAROTITIS AND ORCHITIS 



Salvaneschi has reported that the injection of diphtheria anti- 

 toxin is of considerable value in the treatment of parotitis 

 and in the orchitis frequently complicating parotitis. More re- 

 cently Bonnamour and Bardin have reported 65 cases of mumps which 

 had such treatment (20 c.c. of serum subcutaneously). Of these 57 

 entered the service without a complicating orchitis and none of them 

 developed this complication; in 8 there was testicular pain on admis- 

 sion with a beginning orchitis which resolved promptly after the first 

 or second injection. They consider the serum injections not only 

 of value in the treatment of the orchitis, but as a prophylactic against 

 the development of orchitis. 



PNEUMONIA (LOBAR) 



In the chapter on the Mechanism of the Protein Re- 

 action the effect of injections on the course of lobar pneumonia 

 has been discussed. As we might expect, severe reactions may 

 be followed by a temporary defervescence, but they do not as a rule 

 effect the pulmonary lesion when once it is established. One finds 

 occasional references in the literature in which foreign protein therapy 

 has been used with a measure of success (Monguzzi milk and gono- 

 coccus vaccine, Talamon diphtheria antitoxin, etc.), but the method 

 cannot be considered of established value. On the other hand it is by 

 no means excluded that when specific serum therapy is used (chicken 

 serum, human serum, horse serum), or specific vaccine therapy (as 

 for instance the Rosenow pneumococcus autolysate) part of the thera- 

 peutic effect may not be due to the protein injected. Injections such 

 as those described by Huntoon (soluble antibodies) always bring 

 about a marked reaction on the part of the patient and are effective 

 only when given early in the course of the disease, observations sug- 

 gestive of nonspecific effects. 



PUERPERAL INFECTIONS 



Lindig tried injections of casein in several cases of puerperal in- 

 fection. One case had had a continuous fever for two months. Three 



