INFECTIOUS DISEASES 201 



Kalberlah claims to have obtained very good results by injecting 

 typhoid vaccine. 



Gow has recently used peptone injections for intravenous injections 

 in septicemias and has combined them with subcutaneous injections of 

 streptococcus vaccine (sensitized). By this method he claims to have 

 obtained excellent results; Nolf, too, has had success with peptone 

 injections. 



In two cases of streptococcus sepsis recovery occurred in 4 and 8 

 days respectively after intravenous injection of deutero-albumose. 

 (Liidke.) There was a very severe chill after the injections. In one 

 case of tetragenous sepsis there was prompt recovery after a single 

 injection. 



Among the more recently introduced colloidal metal preparations 

 "argochrom," a methylene-blue-silver combination, seems to have 

 found considerable favor. Wendt treated 14 cases with this agent and 

 considers it of value. 



Weichardt in a recent paper which takes up the effect of protein 

 therapy in the pneumonococcus sepsis of mice, states that both Jaschke 

 and Freund have obtained favorable results in septic cases with protein 

 therapy. 



SMALLPOX 



Holler reports on the treatment of variola with daily intravenous 

 injections of deutero-albumose. The results are described as satisfac- 

 tory. 



TETANUS 



A rather remarkable experience is that reported by Liidke in the 

 treatment of 7 cases of tetanus. These were all cases in which severe 

 spasm had developed after incubation periods of from 7 to 11 days. 

 The treatment consisted of injections of deutero-albumose of from 3 

 to 5 c.c. of a 10% solution, given in 24- or 48-hour intervals. No spe- 

 cific serum and no magnesium sulphate was used. All cases recovered 

 in from 7 to 22 days. Liidke observed the characteristic effect of non- 

 specific therapy on nerve irritability in that the spasms were first aug- 

 mented after the injections, then diminished in intensity. Kaznelson 

 also treated two cases with albumose injections. One case recovered, 

 the other ended fatally. 



TRENCH FEVER 



Paul Jungmann treated a large series of cases of trench fever 

 (Wolhynian Fever) with colloidal metals without result, despite the 

 fact that a typical nonspecific reaction was elicited, with a severe 

 chill, fever, etc. Often the patient was seemingly cured, with the 

 temperature curve normal and the other symptoms in abeyance, but 

 finally the clinical course of the disease again became manifest. 



