MISCELLANEOUS DISEASES 217 



NEPHRITIS 



The albuminuria that accompanies many acute febrile diseases 

 is very promptly influenced by nonspecific injections, according to a 

 number of observers. 



Treatment of a case of pyelonephritis has been reported by Gow, 

 who in this instance made use of a colon-like organism for intra- 

 venous injections. A chill was invariably produced in about 3 to 

 3% hours; there were nausea and headache and the temperature rise 

 usually wert to 103 F. or 104 F. This organism was at first used 

 in a dosage of 50; later 75 and 125 million were injected but the 

 severity of the reaction diminished with successive injections. Thus 

 when the dosage of 75 million was injected the reaction was only 

 to 101.6 F. with some cutaneous hyperesthesia and yawning on the 

 part of the patient. This case of pyelonephrosis made a complete 

 recovery. 



In colon and staphylococcus pyelitis with concomitant bladder 

 irritation Karo has reported very favorable results with injections of 

 terpichin. Similarly in staphylococcus infections of the urinary tract 

 and in the cholecystitis of children the results have been satisfactory. 

 In cases of simple bacteriuria, however, no results were obtained. In 

 the cystitis that accompanies enlarged prostate glands the injections 

 were also found useful. 



NEURITIS 



Dollken has prepared an autolysate of staphylococci and bacillus 

 prodigiosus which has been used rather extensively and is distributed 

 commercially under the name of "vaccinurin." Dollken tried out a 

 series of bacterial extracts, including tuberculin, and vaccines in 

 neuritis and concluded that the combination above mentioned was 

 followed by the best results. From his work he was led to the belief 

 that in heterovaccination we do not deal wholly with a nonspecific 

 plasmaactivation but that there existed a degree of selectivity in the 

 effect of the different vaccines, that is, they were more or less organo- 

 tropic. 



In the first series of neuritic processes (51 cases) treated by him 

 are included both trigeminal and intercostal neuralgia, sciatica, and 

 a large number of neuritides of varying etiology cold, professional, 

 alcoholic, post-typhoidal, luetic, diphtheritic, pressure, facial and 

 radial. He observes that the pressure neuralgias and the so-called 

 rheumatic palsies were the ones most easily influenced. 



Holtzl reports the treatment of some 90 cases with vaccinurin. 

 Of these 61 made complete recoveries and 28 were improved. The 

 series included 25 cases of sciatica of whom 16 made .prompt and com- 

 plete recoveries. The injection was followed by -a systemic effect and 



