228 PROTEIN THERAPY 



exception, were very good. At times an initial intensification of the 

 disease symptoms was observed with the beginning of the treatment, 

 but later this subsided. While the ataxia was not much altered, an 

 increase in the rapidity of transmission of sensory stimuli was ap- 

 parent in all cases and the ability of the patient to work was greatly 

 enhanced. 



An analysis of the results of treatment of the 76 cases follows: 



53 were of the ataxic type 36 were much improved, 17 were 

 slightly improved in walking. 



46 suffered from lancinating pains 38 of these were cured, 5 were 

 improved. 



24 gastric crises of these 23 were cured. 



25 had bladder symptoms 12 were cured, 11 improved. 



Miller is said to have observed that the lancinating pain disap- 

 peared after milk injections (Boas). Wodak treated a number of 

 tabetics with tuberculin and found that the patellar reflex was re- 

 stored in several of his patients after the treatment. Friedlander is 

 said to have obtained a similar result. 



It is to be remembered in this connection that while we may 

 at times improve the symptoms existing in the tabetic, at other times 

 a nonspecific injection may precipitate a gastric crisis or lancinating 

 pains. Schmidt indeed calls attention to this possibility as a mani- 

 festation of the focal activation so frequently observed following non- 

 specific injections. 



Itten tried nonspecific therapy in the treatment of dementia prcecox, 

 treating a series of 9 cases with injections of a 2% solution of rmclein 

 (giving from 0.5 to 1.4 gm.). The cases were not improved. Dollken 

 has treated 21 cases of whom 16 temporarily improved following in- 

 jections of pyocyaneus and dysentery vaccines. 



EPILEPSY 



A number of procedures, essentially nonspecific in character, have 

 been tried in the treatment of epilepsy, beginning with the use of 

 serum injections by Ceni in 1903, brain extract by Lion in 1911, 

 cerebrospinal fluid by Gordon in 1914 and immune rabbit serum 

 by Held. Turner treated 23 cases with colloidal platinum injections 

 and noted a diminution in the number and intensity of the attacks. 



More recently two interesting reports have been published by 

 Dollken and by Edgeworth. 



Dollken used a combined milk and luminal therapy; to the milk 

 injections he added a small amount of vaccine (nonvirulent organisms) 

 and injections were usually given twice a week; after therapeutic 

 improvement took place the number of injections were decreased. 



