DISEASES OF THE EYE 237 



Heinemann and Wilke report excellent results with milk injections in 

 adult blennorrhea and severe eye infections. 



Three rather extensive reports have recently been published, those 

 of Possek, of Berneaud and of Jendralski. Possek (as well as Haab) 

 used a typhoid vaccine, killed with phenol and made up with approxi- 

 mately 500 million organisms to the cubic centimeter. Of this he 

 injected from 0.6 to 1 c.c. subcutaneously the first day and 1 c.c. the 

 second day. Following these injections there was usually a tempera- 

 ture reaction of mild degree. 



This vaccine therapy was applied to a series of eye conditions 

 of undoubted luetic origin, 52 of which were of long standing, 32 of 

 which were recent. Of the old cases 16 were congenital lues, the 

 balance acquired. These cases had had mercury and salvarsan treat- 

 ment for a long time before they were treated with vaccine, but with- 

 out apparent benefit. Possek selected the cases that had not re- 

 sponded to the specific therapy for his experiments with vaccines. 

 In a few cases where no luetic basis was at first suspected and non- 

 specific treatment given without previous specific therapy, excellent 

 results were obtained, although later the luetic nature of the trouble 

 was established serologically. Among these cases, 4 of hereditary 

 keratitis were markedly benefited, the inflammation of the iris re- 

 ceded and the cornea cleared up. In several cases of retinal hemor- 

 rhage the hemorrhage was resorbed, and in cases of turbidity of the 

 lens, a definite clearing was observed. Good results were obtained, 

 too, with optic neuritis. 



A large series of cases (500) have been reported by Berneaud. 

 Berneaud gave over 2,000 injections of milk to these patients and his 

 results are of considerable interest. He obtained little or no result 

 in the treatment of glaucoma, amotio retina?, lacrymal duct inflam- 

 mation, neuritis, neuroretinitis, multiple sclerosis, in keratitis paren- 

 chymatosa or ophthalmoblennorrhea. 



On the other hand, in keratitis eczematosa and scrofulosa, and in 

 secondary glaucoma following iritis marked improvement was noted. 

 In 70 cases of iritis 60 were cured or markedly improved after the 

 injection. In 24 cases of choroiditis 6 were much improved, 10 partly 

 improved and 8 not altered. In his trachoma cases he found that the 

 corneal ulceration was improved while the connective tissue inflamma- 

 tion of the conjunctiva was not much influenced. Of 11 cases of 

 gonorrheal conjunctivitis 9 responded very well. On a concomitant 

 vulvovaginitis in some of these cases there was no apparent effect. 

 Herpes of the cornea was also favorably influenced. 



Jendralski treated 100 cases of eye disease with milk injections. 

 In phlyctenular disease some improvement was observed, more often 

 in the subjective direction than in objective alteration. Trachoma 

 was not altered and in corneal ulceration Jendralski urges great caution 

 lest actual pref oration may follow. In iritis the results were excellent; 



