APPENDIX 



Hofmeister'a Table 



255 



no doubt on the chemical composition of the original protein from 

 which the split products are derived. Kaznelson has reported observa- 

 tions in this connection with protein split products obtained from 

 fibrin, silk, casein, etc., and found that those derived from fibrin were 

 most toxic. 



The Secondary Proteoses or Deutero-albumoses, have been used 

 therapeutically by Liidke and include the protein fragments that are 

 precipitated by complete saturation with ammonium sulphate after 

 the primary proteoses have been removed by half saturation. The 

 group is an indefinite one and includes a number of fragments evi- 

 dently of different sizes which have been classified as A, B and C by 

 Hofmeister, as Thio-albumose, Synalbumose, etc. 



Witte Peptone, which has been frequently studied and which Nolf, 

 Gow and others have made use of for therapeutic injections, consists 

 of a digestion mixture in which albumoses are abundantly found. It 

 is said to be prepared by the digestion of fibrin. From it the primary 

 and secondary proteoses can easily be prepared by salting out in 

 proper concentrations. 



PEPTONES. These are further hydrolytic cleavage products soluble 

 in water, not coagulable by heat nor precipitable by ammonium sul- 

 phate; they are easily diffusible and give biuret reactions. They differ 

 greatly in toxicity. 



PEPTIDS. The simpler compounds of amino-acids, many of which 



