52 PROTOZOA AND DISEASE 



rare i.e., from a pustule of the face of a woman who had 

 a typical thick, discrete eruption eight days old. Such an occur- 

 rence is exceptional, and lymph from that particular case was 

 excluded from the observations, one of which I may now relate. 

 This was made on a specimen of variola lymph simply placed on a 

 clean slide, covered with a cover-glass, and sealed with balsam. At 

 the time nothing but the faint outlines of spherical bodies of different 

 sizes were to be seen. The specimen was put away, and not 

 examined for some months. When I re-examined it at the end of 

 this time all the spherical bodies had disappeared, and every part of 

 the specimen showed, as it still shows, only a fine granular matrix, 



FIG. 14. BODIES RESEMBLING SPORES OF GREGARINES, FORMED IN VARIO 

 LOUS LYMPH SOME TIME AFTER IT HAD BEEN SEALED UP ON A SLIDE. 

 (Camera drawing x 1,000 diameters.) 



in which are embedded numerous pseudonavicella-like bodies, some 

 of which are sketched in Fig. 14, and which may possibly prove to 

 have some connection with the cytoryctes, and hence I give them a 

 place here, though as yet without any definite claim for them. 



One feature of the virus of small-pox and vaccinia is its power of 

 passing under suitable conditions through a Chamberland filter. 

 Siegel, 1 who, among others, has found this to be the case, as shown 

 both by microscopic appearance and inoculation experiments, made 

 at the same time a very careful histological examination of 

 Guarnieri's bodies in the corneae of rabbits, and concluded that they 

 were parasites. Besides this property of passing filters, another has 

 been recently observed, 2 to the effect that if a rabbit is killed twenty- 



1 J. Siegel, Abstract in Brit. Med. Journ., October 21, 1905, Epitome, p. 64. 



2 Aldershoff and Broers, Ann. de VJnst. Pasteur, September 25, 1906. 



