AN ALVEOLAR SARCOMA 99 



the rays of the central chromatic body, the whole supporting the 

 view that the gemmules are formed by a reunion of the chromatic 

 with the achromatic substance. This body may be compared with 

 those named Leydenia gcmmipara by Schaudinn, an example of 

 which is given in Fig. 37 ; 2. The nucleated buds formed by the 

 latter only differ from the gemmules in the former in that the 

 chromatin is condensed in the one and diffused in the other ; the 

 main features as to nuclear body, etc., are essentially the same in 

 the two bodies Fig. 36 ; 7 and 2 respectively. The bodies described 

 by Leyden and Schaudinn 1 occurred in ascitic fluid of a man 

 who had cancer of the stomach and of a girl with some peritoneal 

 growth. Lieberkiihn had previously seen the bodies and mentioned 

 their amoeboid movements. Von Leyden declared them to be parasitic 

 rhizopods, and described them as roundish cells, full of fat-like 

 drops and yellow pigment, usually associated in clusters, which 

 were difficult to separate. They were in lively motion with blunt 

 or pointed pseudopodia, especially on warm days in July. They 

 retained their mobility in fluid which had been kept sterile from 

 three to seven days. Among other features Schaudinn found 

 contractile vacuoles, excretory and other granules. The amoeboid 

 bodies incepted both red and white blood-corpuscles, and fused 

 together without fusion of nuclei (plastogamy). Multiplication was 

 by binary fission and budding. Schaudinn was unable to trace fully 

 the causation of the tumour by the parasites, but thought this 

 connection would eventually be made out. I may here state 

 my opinion that some of the bodies described by Schaudinn as 

 L. gemmipara are identical with phases of the bodies that I have 

 just described in this alveolar sarcoma. I have not found in the 

 amoeboid bodies of this sarcoma any of the evidences of inception 

 of blood-corpuscles mentioned by Schaudinn. In order to express 

 my interpretation of the histological appearances detailed above 

 in the description of this alveolar sarcoma, I cannot do better 

 than direct attention again to the illustrations of granulation tissue 



1 Schaudinn, Sitzungbericht d. Berl. Akad. d. Wiss., 1896, p. 951. 



