INTRODUCTION 



Some writers describe what is called the dispirem stage, in which the 

 daughter-chromosomes unite into a single thread in the form of a loose 

 skein around each attraction-sphere. In any event, after the for- 

 mation of the diaster, all begin to divide, entering on what are called 

 telophases. 



Telophases. The changes that follow the dispirem stage are simple, 

 and constitute the final processes of karyokinesis (telophases). Each 



Fig. 4. Diagram of the later phases of karyokinesis (Wilson). 



G, metaphase : ep, splitting of the chromosomes ; n, the cast-off nucleolus. H, anaphase : if, inter- 

 zonal fibres, or central spindle, between the diverging daughter-chromosomes. /, telophase, showing 

 beginning division of the cell-body, and the mid-body in the equatorial plane of the spindle. _/, division 

 completed. 



collection of chromosomes becomes surrounded with cytoplasm and finally 

 with a membrane ; and thus two daughter-nuclei are formed by division 

 of the original nucleus of the parent-cell. The chromosomes now con- 

 stitute the chromatic substance of the daughter-nuclei, a highly refracting 

 nucleolus is developed and a new attraction-sphere with two centrosomes 

 makes its appearance in the cytoplasm. The parent-cell has become 



