r~ 



A SWEDISH FARMER'S LINEAGE 



61 



In the meanwhile, the disease has appeared in the male ancestor's family, 

 but not in the females, and from this fact we can deduct that the male ancestor 

 must have had the propensity and not the female. A sister of the male ancestor 

 must have had the same propensity, because, when a grandchild of hers, married 

 a grandchild of the male ancestor, two of their several children had this serious 



INHERITANCE SCHEME RELATING TO THE FAMILY DISEASE 

 MYOKLONUS EPILEPSY IN BLEK1NGE. 



\2_ 



/ 



flale aneester 



\ 



female ancestcr 



"" 



\2_ 



v o 



o 



o 



o v @r ', o o K x / o / o o 



flarr'tage between- 

 second cousins 



m 



m 



v o / / o o v x o 



o o ^ / / o o' v 



fla rriagc 



'o o x \ / / o o v 



bclivcc n 



VJ7 



o 



o 



o 



o o 



Vlf 



vm 



Explanation of symbols ( O J. 



denotes n person affected IU///L myoklonus epilepsy (-recessive homozijqot}. 



... hcallhy bul willl proptnsilij (hcttron.iqot ) 



O . . healthy person without propensity ('dominant l<omcu.ijqot). 



disease. Both these parents must therefore have been heterozygots, and the pro* 

 pensity must have originated from the male ancestor and his sister, through one 

 of their parents, but not from the female ancestor, or her family. 



The first bearer of the propensity for myoklonus epilepsy of which we have 

 any information thus lived in the 17th century. There we lose all trace. It is 

 impossible to determine whether the propensity has originated in Sweden, or 

 was brought here from some other country. 



Professor UNVERRICHT in Dorpat was the first to describe the disease in 

 question. 



He has observed several cases in one and the same household in Esthonia. 

 It is not only possible, but very probable that these families living in Sweden 

 and Esthonia, had the same root many years ago, for diseases of this type go in 



