TABLE OF CONTENTS. 



Page. 



List of illustrations " 



Preface .^ ^ 



The discovery of the plague bacillus H 



Morphology of the plague bacillus 13 



Cultivation of the plague bacillus 16 



Nosology and classification 19 



The morbid anatomy and histopathology of plague as described in 



literature 23 



A study of twenty cases of bubonic plague 41 



Group I: Primary uncomplicated bubonic plague 42 



Insects as plague carriers 74 



A new species of rat tlea , "7 



Experiments with flies "9 



A case of bubonic plague in a child, in which the infection was possi- 

 bly carried by pediculi 80 



Group II: Primary bubonic plague with secondary plague septico- 

 pyemia 8" 



Group III : Primary bubonic plague with secondary plague pneumonia 102 



Ambulatory plague or pestis minor. 102 



Group IV : Primary uncomplicated plague pneumonia 108 



Group Y : Primary plague pneumonia with secondary plague septico- 

 pyemia 113 



Group VI: Primary plague septicaemia 11" 



Analysis of the twenty cases reported and summary of the patholog- 

 ical findings 121 



Portal of entrance of the virus 122 



Period of incubation 122 



The lymph glands in bubonic plague 123 



Fibrin formation in the glands and in other organs 125 



Hemorrhages into the bubo and into the distant organs 125 



Plague as a rule not a general microbic infection 127 



The infection of the spleen 128 



The extension of the prima.ry bubo 128 



The other lymph glands 129 



The heart and the circulatory system 129 



The lungs 131 



The spleen - 132 



The genito-urinary system 133 



Hyaline fibrin thrombi of the glomerular capillaries 133 



The urine in plague 13' 



The liver and the gall bladder 139 



The stomach and the intestines 140 



Steps in establishing the post-mortem diagnosis in plague 140 



References to literature 145 



5 



