65 



The other cells in the gland sections are of the nsual type — small 

 mononuclears, plasma cells, mast cells, and neutrophilic and eosino- 

 philic polynuclears. A number of vessels contain a network of 

 fibrin. Such reticula are often seen independently of vessels in 

 several parts of the sections. A continuation of the intravascular 

 fibrin network to the extravascular reticula is nowhere demonstra- 

 ble. The kidneys show profound parench3Tnatous degeneration with 

 cloudy swelling; hyaline glomerular thrombi are not found. The 

 post-mortem changes in the renal tissues are very advanced, so 

 that the finer histological changes are not well preserved. The 

 liver cells are in a condition of cloudy swelling and fatty degenera- 

 tion with both fine and coarse vacuolation. The interacinous con- 

 nective tissue is much increased. The septa contain numerous 

 connective tissue fibers and infiltrating inflammatory cells. This 

 change is so pronounced as to be due evidently not merely to 

 plague infection but to some cause acting before the latter occurred. 

 The interlobular inflammatory foci do not show plague bacilli. 

 The capillaries and veins are much engorged. In the spleen the 

 boundaries of the follicles are generally sharp and the Malpighian 

 bodies are well differentiated from the surrounding tissue. The 

 pulp spaces, however, are not distinct, since they are densely crowded 

 with cellular elements. The red blood corpuscles predominate in 

 number. The different types of leucocytes include many of the 

 large mononuclear cells with large hyaline protoplasm, staining 

 faintly with methylene blue. In the spleen, as in the Ij^mph glands, 

 some of these large hyaline mononuclears contain plague bacilli 

 in their protoplasm. A few of the phagocytes contain other 

 leucocytes or erythroc}i;es. Plague bacilli are only sparingly found 

 in the splenic sections. 



Case No. 8. Inguinal Bubo. 



[Necropsy Protocol No. 965. R. F., native, female, 45 years old, from No. 33 

 Calls Victoria, Intramuros. Died May 7, 1904, at 11.45 p. m., said to have 

 been sick four days. Admitted to San Lazaro Hospital on May 7 at 11.30 

 p. m., and died fifteen minutes later. Post-mortem examination eleven hours 

 after death.] 



The body of a strong, stout woman, about 45 years of age. Post- 

 mortem rigidity is well marked; post-mortem lividity is extensive. 

 There are large livid patches on the anterior surface of the thighs 

 and trunk. No petechise or ecchymoses are seen. The integument 

 shows several old healed cicatrices, which might have been produced 

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