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erythrocytes, and show an increased number of leucocytes. The 

 cells of the lymphatic tissue proper consist of small mononu- 

 clears of the ordinary type and a considerable number of plasma 

 mast cells. Eosinophiles are not seen. Great numbers of plague 

 bacilli are found in the lymph sinus, in the other distinct lymph 

 channels, vessels, and clefts and all over the gland substance. The 

 interior of the most of the blood vessels generally is free from 

 bacilli, although some of the vascular lumina show these organisms 

 in considerable numbers. Gram's stain shows no streptococci in 

 this gland, though smears made from the cervical glands at the 

 post-mortem examination contain typical streptococci. Spleen: 

 The trabecule and the walls of the splenic arteries are thickened; 

 some of the Malpighian corpuscles are still recognizable, although 

 most of them can no longer be distinguished, even those which 

 are preserved being quite small. In general, corpuscles and pulp 

 form one almost structureless mass consisting of a large number 

 of red blood corpuscles and mono- and polynuclear cells. The 

 original pulp spaces can no longer be outlined, and all of the 

 splenic tissue is profusely infiltrated with plague bacilli; however, 

 these are not found in large solid masses, as in the lymph glands, 

 but in small groups. The kidneys show profound parenchymatous 

 degeneration. The lining epithelia of the convoluted tubules have 

 generally lost their nuclei ; the cells as a whole are much swollen and 

 indistinct in outline; and the tubular lumina are more or less 

 obliterated by granular material. The straight tuliules show the 

 same changes, though to a much less degree. The glomeruli do not 

 show such profound changes, and are fairly normal in appearance, 

 though quite a number of plague bacilli are found in some of them. 

 However, these organisms are located, as it appears, not in the 

 glomerular capillaries but between the loops of the tufts. The 

 lymph clefts between the tubules likewise contain plague bacilli, 

 but in moderate numbers only. The liver shows some very small 

 interlobular inflammator}' foci composed of small round cells, and 

 here and there some increase in fibrous connective tissue around 

 the interlobular vessels and bile ducts. The parenchyma cells are 

 finely vacuolated. The capillaries are rather distended but not 

 well filled with blood. In general the hepatic capillaries show 

 very few plague bacilli, except in some places — i. e., those cor- 

 responding to the necrotic foci seen at the autopsy, where we find 

 enormous sausage-like masses of these organisms. They are located 



