LABORATORIES AND PROBLEMS 



practically all the daughter institutes bearing the same 

 name that are now scattered all over the world, have 

 had at least a share of their training in the mother in- 

 stitute here in Paris. 



Of the work of the men who form the regular staff of 

 the Pasteur Institute only a few words need be said 

 here. Doctors Roux, Grancher, Metchnikoff, and 

 Chamberland all had the privilege of sharing Pas- 

 teur's labors during the later years of the master's 

 life, and each of them is a worthy follower of the be- 

 loved leader and at the same time a brilliant original 

 investigator. 1 Roux is known everywhere in connec- 

 tion with the serum treatment of diphtheria, which he 

 was so largely instrumental in developing. Grancher 

 directs the anti-rabic department and allied fields. 

 Metchnikoff , a Russian by birth and Parisian by adop- 

 tion, is famous as the author of the theory that the 

 white blood-corpuscles of the blood are the efficient 

 agents in combating bacteria. Chamberland directs 

 the field of practical bacteriology in its applications to 

 hygiene, including the department in which protective 

 serums are developed for the prevention of various 

 diseases of domesticated animals, notably swine fever 

 and anthrax. About one million sheep and half as 

 many cattle are annually given immunity from an- 

 thrax by the serum here produced. 



Of the patient and unremitting toil demanded of the 

 investigator in this realm of the infinitely little ; of the 

 skill in manipulation, the fertility of resource, the 

 scrupulous exactness of experiment that are absolutely 

 prerequisite to success ; of the dangers that attend in- 

 vestigations which deal with noxious germs, every one 



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