I2I2I2I2.. 



THE HvEMOSPORIDIA OF MAN QI 



fever, &c. The paroxysm of the first day with the same pecu- 

 liarities then sets in only on the third and fifth days ; the 

 paroxysm of the second day is repeated only on the fourth and 

 sixth days, and so on. In a similar manner two or three quartan 

 fevers may combine, and there may be a febris quart ana duplex 

 or triplex. 



In order to demonstrate the combinations of analogous fevers 

 the following table, taken from Mannaberg's work, may prove 

 useful : 



Febris quotidiana simplex. 

 = F. tertiana simplex. 

 = F. quart ana simplex. 

 = F. tertiana duplex. 



123123123 .. .. = F. quartana triplex. 

 120120120.. .. = F. quartana duplex. 



The equivalent figures connected by brackets represent the separate 

 paroxysms of fever, whilst the o represents the afebrile day. 



It has not yet been quite determined whether the so-called 

 BLACKWATER FEVER belongs to the group of malarial fevers, but 

 according to Plehn's statements this appears to be the case, as, 

 at all events at the commencement of the disorder, Haemosporidia 

 are met with in most of the cases : they certainly, however, dis- 

 appear very soon, in consequence of the enormous disintegration 

 of blood corpuscles that takes place in this disease. 



Finally, we speak of " MASKED FORMS of malaria " when there 

 are disturbances of the general health that have a periodical 

 character and yield to quinine. Nevertheless, only those cases 

 should be reckoned as malaria the diagnosis of which is confirmed 

 by the examination of the blood, i.e., by the discovery of Haemo- 

 sporidia. 



Different Haemosporidia correspond to the different types of 

 malaria, and may be regarded either as varieties of one species 

 or as distinct species ; l the latter view appears to be in accordance 

 with the present condition of our knowledge. 



1 In addition to the literature mentioned above, the following may be cited : 

 Golgi, C. ( " Sull' inf. malar." (Arch. p. le. sc. med., 1886, x., p. 104); " Ancora sull 

 inf. mal." (Gaz. d. ospid., 1886, No. 53) ; " Sul ciclo evelutivo dei par. mat. . . ." 

 Arch. p. le sc. med., 1889, xiii., p. 173, and Fortschr. der Med., 1889, No. 3) ; Mar- 



