OPISTHORCHIS FELINEUS 



bourhood of St. Petersburgh who had travelled a great deal in 

 Siberia, and finally by Askanazy in five persons who were natives 

 of the East Prussian district of Heydekrug. In Tomsk Opisthorchis 

 felineus is the most frequent parasite of man that comes under 

 observation at post mortem (6-45 per cent.), whereas Tcenia saginata 

 has only been found in 3^2 per cent., Echino- 

 coccus in 2*4 per cent., Ascaris lumbricoides in i'6 

 per cent., and Oxyuris vermicularis in o - 8 per cent, 

 of the autopsies. In the district of Heydekrug, 

 however, the species in question is also frequent, 

 as in a few years five cases came to our know- 

 ledge (of which three were diagnosed by the dis- 

 covery of the eggs in the faeces). 



In none of Winogradoff's nine 

 cases had the death of the patient 

 been caused direct by the para- 

 sites, yet more or less extensive 

 alterations in the liver were found 

 in all of them ; such as dilatation of 

 the bile ducts with inflammation 

 and thickening of their walls, and 

 centres of inflammation- or atrophy 

 in the liver substance ; icterus 

 was present five times and atrophy 

 of the liver an equal number of 

 times ; ascites was observed three 

 times, and in two cases, probably 

 of recent date, the organ was en- 

 larged. The number of parasites 

 found fluctuated between a few 

 and several hundreds. 



In two of Askanazy's cases, 

 which he examined more closely, 

 a carcinoma was revealed at the 



FIG. 98. Opis- 

 thorchis felineus, 

 Riv., from the 

 liver of the domes- 

 tic cat. Extended 

 specimen for com- 

 parison with D, 

 sibiricum. 



FIG. 97. Dis- 



tovnurn sibiricum, 

 from the liver of 

 man. (AfterWi- 



post mortem, which had developed nogradoff.) 

 at the pjaces most invaded by 

 flukes, so that perhaps there may 



be grounds for the connection which the author seeks to estab- 

 lish between cancer of the liver and the changes induced by the 

 parasites ; these changes consist of numerous and even ramified 

 proliferations of the epithelium of the biliary duct into the con- 

 nective tissue, which is likewise proliferated. The number of worms 



