OF THE " ^V 



VERSITY 1 



OF / 



\^X 79 



iger has given a review of these : in 61 series of experi- 

 ments, 81 calves, heifers, cows and oxen were inoculated 

 with human tuberculosis ; in 41 experiments on 51 ani- 

 mals the result of the inoculation was positive. In 

 many cases the inoculation caused only local processes 

 extending to near-by glands, but the experimental ani- 

 mals were all killed comparatively early, so that the dis- 

 ease could well have spread further if the animals had 

 lived longer. As is known, tuberculosis of cattle fre- 

 quently remains local for a long time. Sometimes the 

 inoculations caused violent tuberculosis in the experi- 

 mental calves, and this was particularly the case when 

 the inoculation material came from patients affected 

 with " feeding tuberculosis. " (Bavenel, Wolff, Fibiger 

 and Jensen, Westenhoeffer.) 



The clinical observations that may be cited in answer 

 to the third question seem to prove that bovine tubercu- 

 losis is transmissible to man. There are many observa- 

 tions, principally upon veterinarians and butchers, of 

 tuberculous inoculation communicated to the hands and 

 fingers through cuts while working with tuberculous 

 organs of cattle. In some cases these were only local 

 lesions that were healed by surgical means; in others, 

 the disease extended to the sheaths of the tendons and 

 glands, and in still others, in the course of time, it 

 appeared to develop into lung tuberculosis. Greater 

 interest attaches to cases of feeding tuberculosis which 

 may with great probability be traced to infection 

 through milk of tuberculous animals. A large number of 

 such cases have been given, from which the following 

 have been chosen : 



1. The 17-year-old daughter of Prof. Gosse died of abdominal 

 tuberculosis after drinking milk from cows affected with udder 

 tuberculosis. Other sources of infection could not be discovered. 



2. Olivier's observation concerns one of the best proven cases 



