INFECTIOUS MASTITIS IN GENERAL 21 



dependent upon the quantity of milk, which is great in one 

 case and small in the other, and thus provides a more or 

 less favorable condition for existence for the bacteria. 



The milk is also changed by the primary lesion. The 

 more widespread and severe the alteration in the udder 

 the greater are the changes in the milk. The casein and 

 fat content of the milk is lessened by degeneration of the 

 parenchymatous cells. The milk is rich in albumin in con- 

 sequence of transudation from the blood stream, shows an 

 increase in cells following desquamation 

 of necrotic epithelium and is of a red 

 color due to retrogressive metamorphosis 

 of the red blood corpuscles. 



The inflammation occurs as a reac- 

 tion to the primary lesion. 



Since the infectious organisms lie in 

 the tubuli, quantities of leucocytes wan- yiq 4 — MUk-infection 

 der into the lumen of those structures. feTb^irs'^^A^utfi^l 



rr<i m • J.1 i? • r, • n /tt^' j\ flammation ( X 150). The 



1 he milk is thereiore rich m cells {hiQ:.4i). epithelial ceiia are swollen 



Q-,--, , . , . . and show weak nuclear 



UANTITY. it the primary lesion is staining (degeneration). 

 , •*■ '' At a few places there are 



Circumscribed, the inflammation is cir- « few layers of ceiis, in- 



' tense cell innltration in 



cumscribed, and if the primary lesion fetfsruefndseverTe'^: 

 is diffuse, the inflammation is hkewise fuS. 1 S ioTon ba' 



J • /*? / TT" J. • J • ja? • cil'i were seen in the 



dlllUSe. (HiXCept in dlllUSe necrosis, tubules by using bacterial 

 r^ 1 , . stains. 



bee later. ) 



Quality. — The exudate is of a suppurative purulent 

 character. The inflammation, following the character of 

 the primary lesion, is purulent catarrhal, purulent croupous, 

 or diphtheritic, sequestrating or apostematous. 



The more virulent the infectious organism the longer 



the inception of the inflammation is deferred, and thus the 



greater the primary lesion will be. The strongly virulent 



infectious organism works repellently upon the leucocytes 



(negative chemotaxis). 



The necrosis produced by the infectious organism how- 



