UDDER-STREPTOMYCOSIS 45 



pus and a thick wall of connective tissue. The walls of 

 the milk-ducts were thickened. 



No. 2: Three weeks after parturition this cow was 

 inoculated in one teat with 10 c.c. of a bouillon culture 

 of streptococci of less virulence, which was also isolated 

 from a case of mastitis and was controlled on two mice, 

 only one of which died in one day. 



On the day after the infection the body temperature 

 was 39.7° C. (ca. 103.5° F.) . The infected quarter of the 

 udder was not noticeably changed. Its milk was of normal 

 appearance but gave a rich yellowish-white purulent sedi- 

 ment which contained few streptococci. 



Two days after the infection the animal was free from 

 fever. The quarter was not visibly altered. Its milk was 

 thick, yellowish-white and gave a rich sediment of yellow- 

 ish-white pus containing few streptococci. 



Three days after the infection the quarter produced 

 decidedly less milk, which was yellowish-white, thick and 

 clumpy. In other respects it was the same as before. 



Five days after the infection the milk of the quarter 

 was yellowish-gray and flocculent, otherwise the same. 



Six days after the infection the quarter was somewhat 

 firmer. It gave a small quantity of milk which was yellow- 

 ish-gray, thick as pulp, puslike and contained but few 

 streptococci. 



Fourteen days after the inoculation the infected quarter 

 and its milk showed the same continued alteration. The 

 animal was then slaughtered. 



Autopsy. — The infected quarter was not markedly 

 swollen, but thick and firm. The milk was yellowish-gray, 

 puslike and thick as pulp. The incision was smeared with 

 the same kind of thick pus. The cut surface was even, 

 yellowish-gray and firm in its lowest part. The lobuli 

 showed no milk points. Upon pressure yellow-gray fibrin 

 plugs were expressed. 



