TERMINAL ORGANS. 



cli 



Fi2. LXXXVI. 



highly complicated in the Pacinian bodies ; and therefore in the further account of 

 them it will be convenient to begin with the former, although the Pacinian bodies 

 have been much longer known. 



a. End-bulbs. Noticed incidentally by Kblliker, but 

 first investigated and recognised as distinct organs by 

 W. Krause, who named them Endkolben. Their figure 

 in man and apes is usually spheroidal (fig. LXXXVI), 

 but oblong in some quadrupeds. They measure about 

 gigth of an inch in diameter, but may exceed this in 

 length with a less breadth, when of an oval shape. 

 They have a simple outer capsule of connective tissue, 

 bearing nuclei, and within this a core of clear soft 

 matter, in which specks resembling fat-granules become 

 visible after exposure to a solution of soda. To an 

 end-bulb there proceeds usually one, but sometimes 

 two, or even three dark-bordered nerve-fibres ; and 

 sometimes an originally single fibre divides into two or 

 three immediately before entering the corpuscle ; or 

 several branches of one fibre may each run into a sepa- 

 rate end-bulb. The fibre or fibres pass into the core, lose 

 their dark borders, and appear to end, when their ends 

 can be traced, in a bulbous extremity or knob. The 



nerve-fibre, when about to enter the corpuscle, is often one nerve-fibre and fat-gra- 

 much coiled, and this may be the case too with its nules in the core. 3. Of an 

 pale continuation within, which contributes greatly to oval figure ; termination of 

 obscure its actual termination. End-bulbs have been 

 hitherto found in the conjunctiva over the sclerotic coat 

 of the eye, and in the mucous membrane on the floor 

 of the mouth, the lips, soft palate, and tongue, being in 

 these last-mentioned situations lodged in papillae, or at 

 their roots ; also, more deeply, in the skin of the glans of the penis and clitoris.* 



Fig. LXXXVII. 



Fig. LXXXVI. THREE 

 NERVE-END-BULBS FROM 

 THE HUMAN CONJUNCTIVA, 

 TREATED WITH ACETIC ACID, 

 MAGNIFIED 300 DIAMETERS. 



1. With two nerve-fibres 

 forming coils within. 2. With 



nerve distinct. Nuclei on 

 the capsules of 1 and 2. 

 (From Kb'lliker, after a draw- 

 ing by Liidden). 



Fig. LXXXVII. END-BULBS IN PAPILLA, MAGNIFIED, 



TREATED WITH ACETIC ACID. 



A, from the lips ; the white loops in one of them 

 are capillaries. B, from the tongue. Two end-bulbs 

 seen in the midst of the simple papillae, a, a, nerves. 

 (From Kbllikev). 



b. Touch-bodies, or tactile corpuscles (corpus- 

 cula tact&s). Discovered by R. Wagner and 

 Meissner. These are mostly of an oval shape, nearly 



* W. Krause has lately described peculiar organs in the skin of the penis and clitoris, 

 allied to the end-bulbs, which he proposes to call genital nerve-corpuscles. They are 

 various in form, but present a mulberry-like surface. One, or two, rarely three or four, 

 dark-bordered nerve-fibres enter each of them. They have a delicate sheath of connec- 

 tive tissue, with many nuclei, and soft finely granular contents allied to the core of the 

 eud-bulbs. 



I 2 



of an inch long, and 



