174 BACTERIOLOGY OF THE EYE 



results of Zur Nedden, who considered Saemisch's section necessary 

 for most cases, perhaps are due to the use of other treatment than 

 zinc. We instil zinc lotion on to the cornea ten or twelve times a 

 day, and also bathe the eye for several minutes in it. It is important 

 that this should be done late in the evening, and in severe cases 

 even repeated several times during the night. The results amply 

 justify the time and trouble taken. In over 'twenty cases, amongst 

 which were several very severe ones, we have obtained healing with 

 zinc alone. A paper by Agricola gives the fuller details of these 

 cases. Paul obtained very good results by repeatedly syringeing the 

 ulcer. He reports that a zinc encrustation once formed, and therefore 

 advises that the use of the solution should not be continued for an 

 unnecessarily long time. 1 We have never had such occur. Without 

 going so far as to say that every case of diplobacillary infection of 

 the cornea must heal with zinc, I personally have never seen it fail. 



Erdmann reported two such failures, but it is not clear how often 

 the zinc was used. A marked infiltration often occurs on the next 

 day even in successful cases ; this is not necessarily a sign of spread, 

 but of a reaction. If advance is not arrested within twenty-four 

 hours, surgical treatment should be adopted. Complications which 

 may arise should be suitably treated. 



Meyerhof states that when trachoma complicates diplobacillary 

 infection (in Egypt), the cases do not react to zinc, and are better 

 treated with silver nitrate. 



LITEEATUEE. 2 



AGRICOLA, Uber eitrige Diplobazillenkeratitis. K. M. f. A., 1906, Beilageheft. 



ALT, Ainer. journ. of ophth., 1898, p. 171. 



ALEXANDER, Munch, med. Woch. , 1903, S. 1236. 



ANDRAD, Amer. journ. of med. sciences, 1902. 



AXENFELD, Heidelberger Kongress, 1896. Zentralbl. f. Bakteriologie, 1897, Bd. 21, 



Nr. 1 and Berliner klin. Wochenschrift, 1897, p. 847. 

 BACH-NEUMANN, A. f. A., 1898, Bd. 37, S. 57. 



BIARD, Etude sur la conjonctivite subaigue. These de Paris, 1897. 

 BIETTI, Annali d' ottalmologia, 1899. 

 BREWERTON, Lancet, 1903, p. 1036. 

 BROWN-PUSEY, Journal of the Amer. Med. Assoc., 1906. 

 BUTLER, R. L. 0. H. Rep., XVII, 1, p. 115. 

 CHRISTENSEN, Ophth. Klinik, 1906, S. 171. 

 COLLINS, TREACHER, Report of the Metropol. Asyl. Board, 1906 (Ref. Miinch. med. 



Woch., 1906, S. 2364). 



1 The translator lias had very good results by both of these methods. In one case an 

 increase in the strength of the zinc solution from to 1 per cent, caused a spread of the 

 ulceration, which subsided when the weaker solution was resumed. 



2 Also see literature on ' General Conjunctivitis.' 



