232 BACTEKIOLOGY OF THE EYE 



suppuration has ceased, there is merely a stage of papillary trachomatous hyper- 

 trophy. As a rule Gonococci cannot be found in this stage, which after some time 

 disappears completely, leaving no scarring. If in a trachomatous country a gonor- 

 rhoaa is directly followed by trachoma (see section on 'Trachoma'), we should 

 consider it a mixed infection. A chronic gonorrhrea, such as would be suggested 

 by the former name of 'chronic blennorrhcea,' is certainly not present in these 

 cases. The fact that, a short time after the subsidence of a gonorrhceal inflam- 

 mation, the Gonococci completely disappear out of the conjunctival sac is certainly 

 no proof that the other Gram-negative Diplococci which we find on the normal 

 conjunctiva are to be considered as Gonococci which have become avirulent. 

 There is just as little justification for the former hypothesis that Gonococci could 

 occasionally be developed out of the other Gram-negative Diplococci; a contagion 

 from without can be proved in almost every case of gonorrhceal inflammation. 



It is very doubtful whether a superimposed gonorrhoea has any curative action 

 on a trachoma, even though an old pannus may be cleared by this means. 

 Gonococcal toxin, which was shown by the experiments of Morax and Elmassian 

 to produce, after an incubation of twenty-four hours, a severe catarrh on continued 

 instillation, could not produce any curative action. 



LITEEATUEE. 



The collected literature up to 1901 can be found in A. f. 0., 1901, Bd. lii., p. 66 ; 

 Groenouw, 'Die Augenentziindungen bei Neugeborenen'; also in ' Ergebnisse,' 

 Lubarsch-Ostertag, by Axenfeld, Sect. 'Bacteriology des Auges,' 1894-1900, Bd. 2, 3, 6 

 (Supplement), continued in 1900-1905 by Zur Nedden; also in Saemisch, 'Hand- 

 buch,' 2nd edit., ' Bindehaut,' p. 216 et seq. 



ABELSDORFF-NEUMANN, A. f. A., 1900, XLII. S. 68. 



BRONS, K. M. f. A., 1907, Bd. I, S. 1. Cf. here the collected literature of Gram- 

 negative Diplococci. 



BUTLER, K. L. O. H. Rep., 1907, XVII, p. 115. 



DALEN, Hygiea, 1899, S. 326. GABRIELIDES, Ophthalm. mikrobiologique, Con- 

 stantinople, 1906, S. 111. La Clin. ophth., 1906, p. 179. 



DAUBER, Zur Prophylaxe der Ophthalmoblennorrhcea neonatorum. Miinch. med. 

 Wochenschr., 1904, S. 297. 



DRUAIS, These de Paris, 1904. 



FRENCH, New York Eye and Ear Infirm. Eef . January, 1897, V. 



HAUPT, tiber gonorrh. und nichtgonorrh. Bindehautentziindung bei Neugeborenen. 

 K. M. f. A., 1903, Bd. XLI, S. 447. 



VON HERFF, Ophthalmoblennorrhcea gonorrhoica. Jahresbericht, Basel, 1904. 



HESS, Miinch. med. Wochenschr., 1904, S. 456. 



KAYSER, B., K. M. f. A., 1903, Bd. 42, T. I, Beilageheft (Festsch.). 



KOBLANK, Meningococcus auf der Bindehaut. Amer. Med. Assoc., Washington, 

 1904. 



KOENIGSTEIN u. L. MILLER, Wien. ophth. Gesellsch., October 25, 1905 (Z. f. A., 

 XV, S. 88). 



KBUKENBERG, K. M. f. A., 1899, Bd. 37, S. 271, 1900, Bd. 38, S. 859, and 1901, 

 Bd. 39, T. II, S. 604. 



LEHMANN-NEUMANN, Bakteriologie, 1904 and 1906. 



McKEE, Blen. Neonat. from B. Coli Comm. Montreal Med. Jour., October, 1906, 



and February, 1907. 



MEYERHOF, K. M. f. A., 1905. XLIII, II, S. 226, and Ann. d'ocul., November, 1906, 

 CXXXVI. 



