238 BACTERIOLOGY OF THE EYE 



perhaps because of it, or the aurens flourishes better on those persons whose 

 tissues are subject to changes such as are present in these conjunctivas and can 

 further develop on them. This latter does really occur, for in the conjunctivitis of 

 measles in many epidemics, at any rate the aureus is very plentiful (Schottelius), 

 though it has primarily nothing to do with the measles or the conjunctivitis. 



The possibility of a change of the ordinary saprophytic Staphylococcus into 

 the pathogenic form, due to a change in the nidus, is still under discussion ; further 

 records can be found (see the collected literature by M. Neisser) concerning such 

 transitions records which in every case do not pay due attention to the sources of 

 error pointed out by Leber, that the white and the yellow Staphylococci may be 

 intimately mixed, and can be transferred together in cultures. It is important to 

 remember that Rupprecht and I have obtained a hgemolytic action from conjunc- 

 tival cocci which appeared to be saprophytic a characteristic which Neisser would 

 only attribute to the pathogenic forms. 



The pigment in the aurens belongs to the group of the Lipochromes, and is 

 insoluble in water. Every bacteriologist knows that its production is very variable, 

 and Neisser considers it possible that the Staph. albus may be a Sta2)h. aureus, 

 which, from some external influence, has lost its pigment. This contention must 

 not be carried too far, for the transference of an aureus into an albus, with its 

 special characteristics, has never yet been successful, and attempts to change a 

 non-liquefying Stapli. albus into an aureus have similarly always failed. 



LITEEATUEE. 



AXENFELD, Deutsche med. Woch., 1898, Nr. 1, and ' Ergebnisse,' 1. c. 



BACH, A. f. O., 1894, Bd. 40, 3. 



BACH-NEUMANN, A. f. A., 1898, 37, S. 93. 



BIETTI, Annali di Ottalmol., 1897. 



CoLLiCA-AccoRDiNO, Supplemento al Policlinico, 1899 (Bef. Michel-Nagel, 1900, 



p. 249). 



COPPEZ, Les conjonctivites pseudomembraneuses, Briissel, 1896. 

 CRAMER, A. f. Gynakol., 1899, Bd. 59, Heft 2. 

 DUANE and HASTINGS, N. Y. Med. Jour., 1906. 

 GASPARRINI, Annali di Ott., 1895, Suppl., p. 30. 

 GONIN, Revue de la Suisse romande, February, 1899. 

 GROENOCW, A. f. O., 1901, Bd. 51. 

 HIROTA, Uber die Mikroorganismen der Conj. catarrh. Inaug. Diss., Halle, 



1902. 



LEBER, SATTLER, Internat. ophth. Kongr., Heidelberg, 1880. 

 LEHMANN-NBUMANN, Bakteriologie, 3 Aufl., 1903. 



LUNDSGAARD, Bakt. Stud, over Konjunktivitis. Kopenhagen, 1900, p. 58. 

 MEIJERS, Inaug. Dissert., Jena, 1900. 

 MICHEL, A. f. A., XVI, 1886 (Trachomcoccus). 

 MORAX, Maladies de la conjunctive. Encyclop. franc, d'ophth. (Valude-Laoran^e 



1905). 



MORAX and ELMASSIAN, Internat. ophth. Kongr., Utrecht. 

 NEISSER, M., and LJPSTEIN, Die Staphylokokken. Handbuch von KOLLE-WASSER- 



MANN, 1903, Bd. 3. 

 POULARD, Infection staphylococcique de la conjonctive. Arch, d'ophth 1905 



p. 603. 



RANDOLPH, Johns Hopkins Hosp. Bull., 1903. 

 ROMER, Z. f. Hyg., 1899, XXXII, Heft 2. 



