SPECIAL FORMS OF CONJUNCTIVAL INFECTION 241 



It should be noticed in this connexion that indol-free strains after prolonged 

 cultivation may eventually produce indol (see Morris, Arch. f. Hyg. u. Infect., 

 1897, Bd. xxx., p. 309). Bacilli which, while showing all the other characteristics, 

 morphological and cultural, show no motility, have no flagellae, and do not form 

 gas, may still be considered as modifications of the Bacterium coli. Gunther and 

 others oppose this view. 



LITEEATUEE. 



AXBNFELD, Ophth. Vers.,, Heidelberg, 1896, Anm., Deutsche med. Woch., 1898, 



Nr. 1. 



BIETTI, K. M. f. A., 1899, S. 311. 



DE BERABDINIS, Annali di Ottalmol., 1904, XXXIII, p. 18. 

 GROENOUW, A. f. 0., 1900, Bd. 52. 

 JARNATOWSKI (polnisch), ref. Michel-Nagel, 1898. 

 McKEE, Montreal Med. Jour., October, 1906. 

 MACNAB, ' Ulceration of the Cornea,' London, 1907. 

 MARKWALD, Zeitschr. f. klin. Med., 1904, Heft 1 & 2. 

 MAZET, These de Paris, 1895. 



MERCANTI, Annali di Ottalmol., 1872, vol. 21, p. 133. 



PANAS, Archives d'ophth., 1897, XVII, p. 273, and Soc. fran9. d'ophth., 1897. 

 PICOT, Archives d'ophth., 1897, XVIII, p. 341. 

 RANDOLPH, Jour. Amer. Med. Ass., 1893, p. 440. 

 SAEMISOH, 2 Aufl. des Handbuchs, 1905. 



TAILOR, U., Lavori della clin. ocul. di Napoli, 1896, vol. 3, p. 273. 

 Vossius, Ophthalmol. Klinik, 1904, Nr. 2. 

 ZUR NEDDEN, K. M. f. A., 1902, XL, Bd. 1, S. 1. 



2. Capsulated Bacilli. The so-called Ozsena Bacillus (Lbwen- 



berg-), and Friedlander's Pneumobacillus. The Bacillus 



Mucosus Capsulatus. 



(PLATE I., FIG. VI.). 



The appearance of the Pneumobacillus is clearly seen from the plates. It forms 

 non-motile plump rods of varying length. 



In the secretion the capsules are always clearly seen, and when deeply stained 

 they take on the dye much more intensely than those of the Pneumococcus. 



It grows on all media even at room temperature. 1 Gelatine stab cultures give a 

 typical ' nail culture,' with a porcelain knob rising over the surface of the medium. 

 No liquefaction of gelatine, but a slight brownish discoloration of the medium. 

 On agar and potatoes a thick white scum ; in sugar media gas formation. No 

 formation of indol ; no spore formation. The cultures are very resistant. 

 Facultative anaerobe. 



Crraw-staining is negative. 



Pathogenic for mouse and dog ; less so for the guinea-pig ; rabbits are not 

 susceptible. This last statement is only true for subcutaneous and intraperitoneal 

 injection. In the vitreous these bacilli cause a severe inflammation (Perles), and 

 they are pathogenic for the cornea and the anterior chamber. 



1 The similar intra- epithelial bacilli, found by Herbert in keratitis punctata superficialis, 

 have not yet been cultivated (see section on ' Keratitis '). 



16 



