THE CORNEA 319 



of the Aspergillus, is explained by the fact that it will only develop in 

 the cornea when it is directly planted into its tissue by a foreign body, 

 or is rubbed into it ; otherwise it can only produce a corneal lesion 

 with difficulty. 



Best 1 records an interesting case of this variety in both eyes of a 

 young blackbird. In the vitreous, the retina, the choroid, the anterior 

 chamber, and the bone of the sclera, there was a dense felt-work of a 

 mould. No cultures were available. Best considered that an injury, 

 perhaps by pecking, was the cause. He recalled the fact that a general 

 experimental infection of the blood with the spores of Aspergillus will 

 readily cause a metastatic infection of the eye. 



In man, too, similar infections of the vitreous by moulds have been 

 described by Leber and Nobbe, Eomer, and Kampherstein. 2 In these 

 cases there was a necrosis in the immediate vicinity of the mycelium, 

 and around that a suppuration. Leber and Nobbe, as well as Rollet 

 and Aurand, have produced the same result by experimental infection 

 of the vitreous. In the vitreous no reproductive organs were formed. 

 In a phthisical eye Schirmer has demonstrated microscopically the 

 presence of a mould infection passing from the cornea into the 

 interior. 



Koellner, in Michel's clinic, described a mould infection of the 

 sclera with partial necrosis. Here, too, there was a sequestrum 

 formed. The nature of the mould could not be determined by 

 cultures. 



LITEEATUEB. 



The literature up to, and including, 1903 is given by Kayser and by Johnson in 

 the K. M. f. A., 1903, XLI, I, p. 50, and XLI, II, p. 206. 



BAQUIS, Una nuova forma di cheratomicosi. Annali di Ottalmol., 1905, XXXIV, 



p. 945. 



BUCHANAN, Mycosis of the eyeball. Glasgow Med. Journ., December, 1905. 

 KAMPHERSTEIN, K. M. f. A., 1903, XLI, I, S. 151 (here is the literature of mould 



infections of the vitreous). 



KOELLNER, Schimnielpilzinfektion der Sklera. Z. f. A., 1906, XLI, S. 441. 

 MARTIN, A. f. A., 1904, L, S. 177. 

 OSTERROTH, Berl. klin. Woch., 1905, Nr. 7. 

 ROLLET et AURAND, Experiment. Aspergilluskeratitiden. Revue generale d'ophth., 



July, 1906 (K. M. f. A., 1905, I, S. 774), and Rev. gener., 1907, S. 1. 

 ROSENSTEIN, Ein schimmliges Geschwtir der Lidhaut. Zentralbl. f. A., January, 



1901. 

 ZADE, A. f. O., 1907, LXV, p. 41, etc. 



1 Deutsche Med. Wpch., 1905, S. 1821. 



2 Aspergillus fumigatus occurred in Leber-Nobbe and Homer's cases; in Kampherstein's 

 case the organism was doubtful. 



