THE MICROSCOPE IN PATHOLOGY. 



241 



hepatic cells in the region of the portal vein, until the 

 whole organ may ultimately have twice as much solid 

 albuminous substance as normal, and becomes pale gray 

 in color, translucent, and of vvaxlike consistence (Fig. 195). 



2. Calcification. 



Calcification is the infiltration of tissue with solid phos- 

 phate or carbonate of lirne. Free carbonic acid is solvent 

 of these salts, and by its capacity for diffusion it escapes, 

 leaving the insoluble salts in the nutritive fluid. 



Thus cartilage normally becomes bone, and under pecu- 

 liar circumstances other tissues ossify. True osseous tis- 

 sue, however, differs greatly from mere calcification by 



FIG. I9fi. 



Arthritis uratica. Vertical section through a superficial articular body infiltrated with 

 urate of lime. a. The surface. 6. Cartilage cavities with tufts of crystals, c. Cartilage 

 cells not yet infiltrated, in division, d. Isolated needles of crystals in the basis-substance. 

 After CORNEIL ET EANVIER. 



the arrangement of its solid particles (see page 195). 

 Calcification of arteries is a secondary affection, succeed- 

 ing to fatty degeneration of the connective tissue. 



Analogous to calcification is the arthritic deposit of 



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