THE MICROSCOPE IN PATHOLOGY. 



247 



itself without the intervention of the nerves or the blood, 

 which is excited to increased nutritive activity, to greater 

 metamorphosis, and to new formation ; and the more 

 quickly this takes place, the more it runs the danger of de- 

 struction, the more is the process to be looked on as in- 

 flammatory. There may be truth in both these views, 

 since the nutrition of the cell is so greatly influenced by 

 nerve action. 



The second phenomenon of inflammation is exudation 

 and suppuration. The most disputed point respecting in- 

 flammation has been the genesis of pus-corpuscles. We 

 have seen, page 189, that they are identical in the living 

 state wuh leucocytes, or white blood-cells. In other words, 

 they are merely particles of bioplasm. Their migration 



FIG. 202. 



Cohnheim's experiment, a. Vein, b b. Contiguous connective tissue, permeated by 

 migrating colorless blood-corpuscles, c. Column of red blood-corpuscles. 1-500. After 



RlNDFLEISCH. 



through the walls of bloodvessels was first described by 

 Dr. Addison in 1842, and afterwards, in 1846, by Dr. 

 Waller. These observations w^ere forgotten, however, un- 

 til 1867, when Professor Cohnheim, of Berlin, showed the 



