THE MICROSCOPE IN PATHOLOGY. 251 



mass of germinal matter increases in size and soon begins 

 to divide into smaller portions. Parts seem to move away 

 from the general mass. These at length become detached, 

 and thus several separate masses of germinal matter, 

 which are imbedded in the softened and altered formed 

 material, result. In this way the so-called inflammatory 

 product pus results. 



"It will be seen how easily the nature of the changes 

 occurring in cells in inflammation can be explained if the 

 artificial nomenclature of cell-wall, cell-contents, nucleus 

 be given up. In all acute internal inflammations a much 

 larger quantity of inanimate pabulum is taken up by cer- 

 tain cells and converted into living matter than in the 

 normal state. Hence there is increase in bulk; cells of 

 particular organs, w r hich live slowly in health, live very 

 fast in certain forms of disease. More pabulum reaches 

 them, and they grow -more rapidly in consequence. 



"In cells which have been growing very rapidly and 

 are returning to their normal condition, in which the access 

 of nutrient pabulum is more restricted than in the abnormal 

 state, as is the case in normal cells passing from the em- 

 bryonic to the fully formed state, the outer part of the 

 germinal matter undergoes conversion into formed mate- 

 rial, and this last increases as the supply of pabulum be- 

 comes reduced. 



" We will now inquire what alterations can be observed 

 in cells, the ''formed material' of which, under normal con- 

 ditions, becomes quickly resolved into other soluble con- 

 stituents if these cells be placed under circumstances 

 which caused the formed material to become harder and 

 less permeable to nutrient matter than in health. The 

 formed material which enters into the formation of the 

 liver-' cell' is soft, moist, and readily permeable to certain 

 nutrient matters. There is no cell-wall, but the outer 

 part of the formed material is gradually resolved into 

 soluble biliary matters, which pass down the ducts, and 



