THE MICROSCOPE IN PATHOLOGY. 287 



with in the subjacent connective tissue. Yet a simple 

 papilloma may develop into an epithelioma. 



2. Adenoma, or Glandular Tumor. This forms sharply 

 defined, and generally encapsuled, knots of new-formed 

 glandular tissue. Its structure resembles that of race- 

 mose or tubular glands, and consists of numerous saccules 

 or tubes lined with squamous or cylindrical epithelial 

 cells. These are grouped together, being separated by a 

 small amount of vascular connective tissue. 



As sarcomata, myxomata, etc., occurring in glandular 

 organs, have more or less glandular tissue, it is often dif- 

 ficult to see which predominates, hence the terms adeno- 

 sarcoma, adeno-myxoma, etc. 



Adenomata of the skin vary in size to that of an egg, 

 and originate from sweat or sebaceous glands. Rlnd- 

 fleisch considers lupus to be of this nature (see Lupus). 



Adenomata of mucous membranes form mucous polypi, 

 which are usually broad, rarely pedunculated, and grow 

 from the size of a bean to that of a hen's egg. The sur- 

 face of such tumors is like that of the mucous membrane, 

 but internally it may be fibrous and vascular, or even 

 cystic. They occur on all mucous membranes, but often- 

 est in the nasal cavity, rectum, and uterus. The conse- 

 quences of these adenomata depend on their size and 

 anatomical relations. Thus they may form obstructions 

 and give rise to catarrh and haemorrhage. 



Adenomata of glands occur more especially in the 

 mamma, parotid, prostate, liver, and thyroid. Adenoma 

 of the thyroid is known as goitre. Adenoma of the 

 mamma (Fig. 234) is called by Bill roth a " true epithelial 

 glandular carcinoma." The only difference between it 

 and a genuine epithelioma or carcinoma appears to be 

 that the proliferatien of the epithelium is confined to the 

 dilated glandular cavities, instead of infiltrating the sepa- 

 rating walls, as in cancer. 



Some ovarian cysts myxoid or colloid cystomata 



